Breast cancer in young patients. Peculiarities of prognosis and adjuvant hormone therapy (a literature review)
Breast cancer (BC) keeps being the most predominant malignant disease in women. In recent years, a trend towards “rejuvenescence” of the disease has been observed that affects its features. Despite modern methods of diagnosis and complex treatment used in young patients, survival in this age group a...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | Russian |
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ABV-press
2018-10-01
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| Series: | Опухоли женской репродуктивной системы |
| Subjects: | |
| Online Access: | https://ojrs.abvpress.ru/ojrs/article/view/607 |
| _version_ | 1797876016975183872 |
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| author | D. N. Kravchenko A. A. Parokonnaya M. I. Nechushkin E. A. Nikitina N. D. Hakurinova |
| author_facet | D. N. Kravchenko A. A. Parokonnaya M. I. Nechushkin E. A. Nikitina N. D. Hakurinova |
| author_sort | D. N. Kravchenko |
| collection | DOAJ |
| description | Breast cancer (BC) keeps being the most predominant malignant disease in women. In recent years, a trend towards “rejuvenescence” of the disease has been observed that affects its features. Despite modern methods of diagnosis and complex treatment used in young patients, survival in this age group are inferior that’s associated with biological and morphological peculiarities of BC in young age. Gradually are being collected data according to what age might be an independent factor exacerbating prognosis. For BC patients younger 40 years, various aspectsof hormone therapy remain ambiguous: prolonged tamoxifen use, aromatase inhibitors prescription, ovarian function suppression, a role of chemotherapy-induced amenorrhea on prognosis. The issue of appropriate, personalized adjuvant hormone therapy of BC is complex and heterogenous that requires a necessity to further conduct international randomized trials. |
| first_indexed | 2024-04-10T01:56:39Z |
| format | Article |
| id | doaj.art-9c2a5131bf344caba46f4339ff749ccd |
| institution | Directory Open Access Journal |
| issn | 1994-4098 1999-8627 |
| language | Russian |
| last_indexed | 2024-04-10T01:56:39Z |
| publishDate | 2018-10-01 |
| publisher | ABV-press |
| record_format | Article |
| series | Опухоли женской репродуктивной системы |
| spelling | doaj.art-9c2a5131bf344caba46f4339ff749ccd2023-03-13T08:44:36ZrusABV-pressОпухоли женской репродуктивной системы1994-40981999-86272018-10-01143556310.17650/1994-4098-2018-14-3-55-63587Breast cancer in young patients. Peculiarities of prognosis and adjuvant hormone therapy (a literature review)D. N. Kravchenko0A. A. Parokonnaya1M. I. Nechushkin2E. A. Nikitina3N. D. Hakurinova4ФГБУ «Национальный медицинский исследовательский центр онкологии им. Н.Н. Блохина» Минздрава РоссииФГБУ «Национальный медицинский исследовательский центр онкологии им. Н.Н. Блохина» Минздрава РоссииФГБУ «Национальный медицинский исследовательский центр онкологии им. Н.Н. Блохина» Минздрава РоссииФГБУ «Национальный медицинский исследовательский центр онкологии им. Н.Н. Блохина» Минздрава РоссииФГБУ «Национальный медицинский исследовательский центр онкологии им. Н.Н. Блохина» Минздрава РоссииBreast cancer (BC) keeps being the most predominant malignant disease in women. In recent years, a trend towards “rejuvenescence” of the disease has been observed that affects its features. Despite modern methods of diagnosis and complex treatment used in young patients, survival in this age group are inferior that’s associated with biological and morphological peculiarities of BC in young age. Gradually are being collected data according to what age might be an independent factor exacerbating prognosis. For BC patients younger 40 years, various aspectsof hormone therapy remain ambiguous: prolonged tamoxifen use, aromatase inhibitors prescription, ovarian function suppression, a role of chemotherapy-induced amenorrhea on prognosis. The issue of appropriate, personalized adjuvant hormone therapy of BC is complex and heterogenous that requires a necessity to further conduct international randomized trials.https://ojrs.abvpress.ru/ojrs/article/view/607рак молочной железымолодой возрастгормонотерапияхимиотерапияовариальная супрессия |
| spellingShingle | D. N. Kravchenko A. A. Parokonnaya M. I. Nechushkin E. A. Nikitina N. D. Hakurinova Breast cancer in young patients. Peculiarities of prognosis and adjuvant hormone therapy (a literature review) Опухоли женской репродуктивной системы рак молочной железы молодой возраст гормонотерапия химиотерапия овариальная супрессия |
| title | Breast cancer in young patients. Peculiarities of prognosis and adjuvant hormone therapy (a literature review) |
| title_full | Breast cancer in young patients. Peculiarities of prognosis and adjuvant hormone therapy (a literature review) |
| title_fullStr | Breast cancer in young patients. Peculiarities of prognosis and adjuvant hormone therapy (a literature review) |
| title_full_unstemmed | Breast cancer in young patients. Peculiarities of prognosis and adjuvant hormone therapy (a literature review) |
| title_short | Breast cancer in young patients. Peculiarities of prognosis and adjuvant hormone therapy (a literature review) |
| title_sort | breast cancer in young patients peculiarities of prognosis and adjuvant hormone therapy a literature review |
| topic | рак молочной железы молодой возраст гормонотерапия химиотерапия овариальная супрессия |
| url | https://ojrs.abvpress.ru/ojrs/article/view/607 |
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