The Expression of Cell Cycle-Related Genes in <i>USP8</i>-Mutated Corticotroph Neuroendocrine Pituitary Tumors and Their Possible Role in Cell Cycle-Targeting Treatment

The Expression of Cell Cycle-Related Genes in <i>USP8</i>-Mutated Corticotroph Neuroendocrine Pituitary Tumors and Their Possible Role in Cell Cycle-Targeting Treatment

Protein deubiquitinases <i>USP8</i> and <i>USP48</i> are known driver genes in corticotroph pituitary neuroendocrine tumors (PitNETs). <i>USP8</i> mutations have pleiotropic effects that include notable changes in genes’ expression. Genes involved in cell cycle re...

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Bibliographic Details
Main Authors: Beata Joanna Mossakowska, Natalia Rusetska, Ryszard Konopinski, Paulina Kober, Maria Maksymowicz, Monika Pekul, Grzegorz Zieliński, Andrzej Styk, Jacek Kunicki, Mateusz Bujko
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Cancers
Subjects:
Cushing’s disease
corticotroph PitNET
pituitary
<i>USP8</i>
<i>USP48</i>
cell cycle
Online Access:https://www.mdpi.com/2072-6694/14/22/5594

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