Transcriptomic Effects of LINC01614 on Lung Cancer A549 Cells and Relevance of Drug Resistance

Transcriptomic Effects of LINC01614 on Lung Cancer A549 Cells and Relevance of Drug Resistance

Objective To investigate the biological role of LINC01614 in non-small cell lung cancer A549 cells and its drug resistance-related mechanism. Methods The CRISPR/Cas9 technology was used to construct the A549 cell model with knockdown of LINC01614. Transcriptome sequencing was performed on A549 cells...

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Bibliographic Details
Main Authors: BAI Yuming, LI Jin, SHI Lin, JIA Yongfeng, LIU Xia, YUN Fen
Format: Article
Language:zho
Published: Magazine House of Cancer Research on Prevention and Treatment 2023-06-01
Series:Zhongliu Fangzhi Yanjiu
Subjects:
linc01614
non-small cell lung cancer
transcriptome sequencing
cisplatin
drug resistance
Online Access:http://www.zlfzyj.com/EN/10.3971/j.issn.1000-8578.2023.22.0293

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