Mucosal Immunization Has Benefits over Traditional Subcutaneous Immunization with Group A Streptococcus Antigens in a Pilot Study in a Mouse Model

Mucosal Immunization Has Benefits over Traditional Subcutaneous Immunization with Group A Streptococcus Antigens in a Pilot Study in a Mouse Model

Group A Streptococcus (GAS) is a major human pathogen for which there is no licensed vaccine. To protect against infection, a strong systemic and mucosal immune response is likely to be necessary to prevent initial colonization and any events that might lead to invasive disease. A broad immune respo...

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Bibliographic Details
Main Authors: Helen Alexandra Shaw, Alex Remmington, Giselle McKenzie, Caroline Winkel, Fatme Mawas
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Vaccines
Subjects:
group A Streptococcus
strep A
<i>Streptococcus pyogenes</i>
vaccines
multicomponent
mucosal
Online Access:https://www.mdpi.com/2076-393X/11/11/1724

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