Clinical variants of the metabolic syndrome in young people living in the Khanty-Mansiysk autonomous region – Yugra
Currently the “rejuvenation” and an increase in the number of components of the metabolic syndrome (MS) determine its clinical significance in the earlier development of diabetes mellitus, cardiovascular diseases and related complications. Aim of the study was to investigate the features of the MS c...
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| Format: | Article |
| Language: | Russian |
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Russian Academy of Sciences, Siberian Branch Publishing House
2024-01-01
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| Series: | Сибирский научный медицинский журнал |
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| Online Access: | https://sibmed.elpub.ru/jour/article/view/1319 |
| _version_ | 1797269544261124096 |
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| author | E. V. Korneeva M. I. Voevoda |
| author_facet | E. V. Korneeva M. I. Voevoda |
| author_sort | E. V. Korneeva |
| collection | DOAJ |
| description | Currently the “rejuvenation” and an increase in the number of components of the metabolic syndrome (MS) determine its clinical significance in the earlier development of diabetes mellitus, cardiovascular diseases and related complications. Aim of the study was to investigate the features of the MS clinic picture in a population of young men and womenliving in the Khanty-Mansiysk autonomous region – Yugra.Material and methods. The study included 863 young people between 18 and 44 years of age, including 344 men and women with MS and 519 people in the comparison group. Studied subgroups are represented by non-indigenous men and women living in urban and rural areas, and indigenous rural residents. The analysis of MS clinical and laboratory parameters was carried out and its clinical variants in ethnic groups were identified.Results and its discussion. According to the results of the survey of young people with metabolic syndrome, it was revealed that the combination of abdominal obesity and two components of MS were most common in young people with MS (in 50.0 % men and in 55.5 % women). The study defined regression models for each MS group and threshold values for waist circumference were set, which changes in lipid and carbohydrate metabolism were predicted.Conclusions. In groups with MS, hypertriglyceridemia was determined as its most common component. The study identified the most frequent association of abdominal obesity with hyper-LDL cholesterol and hypertriglyceridemia in patients with metabolic syndrome, in ethnic groups, this combination is more common in indigenous rural men (53.3 %) and in non-indigenous urban women (54.3 %). |
| first_indexed | 2024-03-08T14:33:10Z |
| format | Article |
| id | doaj.art-9c4638ad22444ac48e7a3b00447d4f38 |
| institution | Directory Open Access Journal |
| issn | 2410-2512 2410-2520 |
| language | Russian |
| last_indexed | 2024-04-25T01:50:04Z |
| publishDate | 2024-01-01 |
| publisher | Russian Academy of Sciences, Siberian Branch Publishing House |
| record_format | Article |
| series | Сибирский научный медицинский журнал |
| spelling | doaj.art-9c4638ad22444ac48e7a3b00447d4f382024-03-07T18:50:01ZrusRussian Academy of Sciences, Siberian Branch Publishing HouseСибирский научный медицинский журнал2410-25122410-25202024-01-0143613814710.18699/SSMJ20230617569Clinical variants of the metabolic syndrome in young people living in the Khanty-Mansiysk autonomous region – YugraE. V. Korneeva0M. I. Voevoda1Surgut State UniversityFederal Research Center for Fundamental and Translational MedicineCurrently the “rejuvenation” and an increase in the number of components of the metabolic syndrome (MS) determine its clinical significance in the earlier development of diabetes mellitus, cardiovascular diseases and related complications. Aim of the study was to investigate the features of the MS clinic picture in a population of young men and womenliving in the Khanty-Mansiysk autonomous region – Yugra.Material and methods. The study included 863 young people between 18 and 44 years of age, including 344 men and women with MS and 519 people in the comparison group. Studied subgroups are represented by non-indigenous men and women living in urban and rural areas, and indigenous rural residents. The analysis of MS clinical and laboratory parameters was carried out and its clinical variants in ethnic groups were identified.Results and its discussion. According to the results of the survey of young people with metabolic syndrome, it was revealed that the combination of abdominal obesity and two components of MS were most common in young people with MS (in 50.0 % men and in 55.5 % women). The study defined regression models for each MS group and threshold values for waist circumference were set, which changes in lipid and carbohydrate metabolism were predicted.Conclusions. In groups with MS, hypertriglyceridemia was determined as its most common component. The study identified the most frequent association of abdominal obesity with hyper-LDL cholesterol and hypertriglyceridemia in patients with metabolic syndrome, in ethnic groups, this combination is more common in indigenous rural men (53.3 %) and in non-indigenous urban women (54.3 %).https://sibmed.elpub.ru/jour/article/view/1319metabolic syndromedyslipidemiahypertriglyceridemiahyperglycemiaarterial hypertensionindigenous peoples of the far north |
| spellingShingle | E. V. Korneeva M. I. Voevoda Clinical variants of the metabolic syndrome in young people living in the Khanty-Mansiysk autonomous region – Yugra Сибирский научный медицинский журнал metabolic syndrome dyslipidemia hypertriglyceridemia hyperglycemia arterial hypertension indigenous peoples of the far north |
| title | Clinical variants of the metabolic syndrome in young people living in the Khanty-Mansiysk autonomous region – Yugra |
| title_full | Clinical variants of the metabolic syndrome in young people living in the Khanty-Mansiysk autonomous region – Yugra |
| title_fullStr | Clinical variants of the metabolic syndrome in young people living in the Khanty-Mansiysk autonomous region – Yugra |
| title_full_unstemmed | Clinical variants of the metabolic syndrome in young people living in the Khanty-Mansiysk autonomous region – Yugra |
| title_short | Clinical variants of the metabolic syndrome in young people living in the Khanty-Mansiysk autonomous region – Yugra |
| title_sort | clinical variants of the metabolic syndrome in young people living in the khanty mansiysk autonomous region yugra |
| topic | metabolic syndrome dyslipidemia hypertriglyceridemia hyperglycemia arterial hypertension indigenous peoples of the far north |
| url | https://sibmed.elpub.ru/jour/article/view/1319 |
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