Emerging role of microRNAs in diagnosis and treatment of various diseases including ovarian cancer
<p>Abstract</p> <p>MicroRNAs (miRNAs) represent a class of small non-coding RNAs that control gene expression by targeting messenger RNA (mRNA). Recently, it has been demonstrated that miRNA expression is altered in many human diseases including cancers, suggesting that miRNA may p...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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BMC
2009-08-01
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| Series: | Journal of Ovarian Research |
| Online Access: | http://www.ovarianresearch.com/content/2/1/11 |
| _version_ | 1797969214706810880 |
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| author | Shah Parag P Hutchinson Lauren E Kakar Sham S |
| author_facet | Shah Parag P Hutchinson Lauren E Kakar Sham S |
| author_sort | Shah Parag P |
| collection | DOAJ |
| description | <p>Abstract</p> <p>MicroRNAs (miRNAs) represent a class of small non-coding RNAs that control gene expression by targeting messenger RNA (mRNA). Recently, it has been demonstrated that miRNA expression is altered in many human diseases including cancers, suggesting that miRNA may play a potential role in the pathogenesis of different diseases. It has also been reported that there is a unique expression pattern of miRNAs in the disease state differing from the normal state. In this review, we focus on the miRNA signatures in different human diseases including cancers. Such signatures may be used as diagnostic and prognostic markers.</p> |
| first_indexed | 2024-04-11T02:57:33Z |
| format | Article |
| id | doaj.art-9c4a49c98e354ad2a6c19e6f9bc341b6 |
| institution | Directory Open Access Journal |
| issn | 1757-2215 |
| language | English |
| last_indexed | 2024-04-11T02:57:33Z |
| publishDate | 2009-08-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Ovarian Research |
| spelling | doaj.art-9c4a49c98e354ad2a6c19e6f9bc341b62023-01-02T14:36:45ZengBMCJournal of Ovarian Research1757-22152009-08-01211110.1186/1757-2215-2-11Emerging role of microRNAs in diagnosis and treatment of various diseases including ovarian cancerShah Parag PHutchinson Lauren EKakar Sham S<p>Abstract</p> <p>MicroRNAs (miRNAs) represent a class of small non-coding RNAs that control gene expression by targeting messenger RNA (mRNA). Recently, it has been demonstrated that miRNA expression is altered in many human diseases including cancers, suggesting that miRNA may play a potential role in the pathogenesis of different diseases. It has also been reported that there is a unique expression pattern of miRNAs in the disease state differing from the normal state. In this review, we focus on the miRNA signatures in different human diseases including cancers. Such signatures may be used as diagnostic and prognostic markers.</p>http://www.ovarianresearch.com/content/2/1/11 |
| spellingShingle | Shah Parag P Hutchinson Lauren E Kakar Sham S Emerging role of microRNAs in diagnosis and treatment of various diseases including ovarian cancer Journal of Ovarian Research |
| title | Emerging role of microRNAs in diagnosis and treatment of various diseases including ovarian cancer |
| title_full | Emerging role of microRNAs in diagnosis and treatment of various diseases including ovarian cancer |
| title_fullStr | Emerging role of microRNAs in diagnosis and treatment of various diseases including ovarian cancer |
| title_full_unstemmed | Emerging role of microRNAs in diagnosis and treatment of various diseases including ovarian cancer |
| title_short | Emerging role of microRNAs in diagnosis and treatment of various diseases including ovarian cancer |
| title_sort | emerging role of micrornas in diagnosis and treatment of various diseases including ovarian cancer |
| url | http://www.ovarianresearch.com/content/2/1/11 |
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