Randomised trial of intravenous thiamine and/or magnesium sulphate administration on erythrocyte transketolase activity, lactate concentrations and alcohol withdrawal scores

Randomised trial of intravenous thiamine and/or magnesium sulphate administration on erythrocyte transketolase activity, lactate concentrations and alcohol withdrawal scores

Abstract Alcohol withdrawal syndrome (AWS) occurs in 2% of patients admitted to U.K. hospitals. Routine treatment includes thiamine and benzodiazepines. Laboratory studies indicate that thiamine requires magnesium for optimal activity, however this has not translated into clinical practice. Patients...

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Bibliographic Details
Main Authors: Donogh Maguire, Alana Burns, Dinesh Talwar, Anthony Catchpole, Fiona Stefanowicz, David P. Ross, Peter Galloway, Alastair Ireland, Gordon Robson, Michael Adamson, Lesley Orr, Joanna-Lee Kerr, Xenofon Roussis, Eoghan Colgan, Ewan Forrest, David Young, Donald C. McMillan
Format: Article
Language:English
Published: Nature Portfolio 2022-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-10970-x

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