Topically applied pH-responsive nanogels for alkyl radical-based therapy against psoriasiform hyperplasia

Topically applied pH-responsive nanogels for alkyl radical-based therapy against psoriasiform hyperplasia

AbstractPhototherapy is a conventional antipsoriatic approach based on oxygen-relevant generation of oxidative stress to inhibit keratinocyte hyperproliferation. However, this therapy can be restricted due to local hypoxia in psoriatic lesions. The generation of alkyl radicals is oxygen-independent...

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Bibliographic Details
Main Authors: G.R. Nirmal, Chia-Chih Liao, Zih-Chan Lin, Abdullah Alshetaili, Erica Hwang, Shih-Chun Yang, Jia-You Fang
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Drug Delivery
Subjects:
Nanogel
chitosan
pH-responsiveness
skin delivery
alkyl radical
psoriasis
Online Access:https://www.tandfonline.com/doi/10.1080/10717544.2023.2245169

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