Treatment of an Early Kaposi’s Sarcoma Case Post Kidney Transplantation by Sirolimus: A Case Report

Kaposi᾽s sarcoma (KS) can develop in 0.06% to 4.1% of kidney transplant recipients. Here we describe a case of 50-year-old man who developed KS a few months after kidney transplantation. After transplantation, he had delayed graft function and was managed by anti-thymocyte globulin (ATG) for five da...

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Main Authors: Farzaneh Najafi, Parichehr Kafaie, Hossein Neamatzadeh
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2017-02-01
Series:Acta Medica Iranica
Subjects:
Online Access:https://acta.tums.ac.ir/index.php/acta/article/view/5156
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author Farzaneh Najafi
Parichehr Kafaie
Hossein Neamatzadeh
author_facet Farzaneh Najafi
Parichehr Kafaie
Hossein Neamatzadeh
author_sort Farzaneh Najafi
collection DOAJ
description Kaposi᾽s sarcoma (KS) can develop in 0.06% to 4.1% of kidney transplant recipients. Here we describe a case of 50-year-old man who developed KS a few months after kidney transplantation. After transplantation, he had delayed graft function and was managed by anti-thymocyte globulin (ATG) for five days. At the discharge, his immunosuppressive therapy was prednisolone 20 mg/day, tTacrolimus (Pprograf®) 4 mg/day, and mycophenolate mofetil (MMF) 2 gr/day, while he also took Vvalcyte and diltiazem. Once diagnosed with KS, the Prograf® (tacrolimus)  was replaced by prednisolone (5 mg/day) and sirolimus (2 mg/day). Gradually the skin nodule on the patient arm disappeared, and the others nodule on the right his leg was decreased. It seems that the examination of skin should be a part of regular follow-up and dermatologist examination is recommended every 6 months.
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spelling doaj.art-9c53f533465e4333bd77146fd87b0ad52022-12-22T00:24:30ZengTehran University of Medical SciencesActa Medica Iranica0044-60251735-96942017-02-015525126Treatment of an Early Kaposi’s Sarcoma Case Post Kidney Transplantation by Sirolimus: A Case ReportFarzaneh Najafi0Parichehr Kafaie1Hossein Neamatzadeh2Department of Internal Medicine, School of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.Department of Dermatology, School of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.Mother and Newborn Health Research Center, Shahid Sadoughi Hospital, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.Kaposi᾽s sarcoma (KS) can develop in 0.06% to 4.1% of kidney transplant recipients. Here we describe a case of 50-year-old man who developed KS a few months after kidney transplantation. After transplantation, he had delayed graft function and was managed by anti-thymocyte globulin (ATG) for five days. At the discharge, his immunosuppressive therapy was prednisolone 20 mg/day, tTacrolimus (Pprograf®) 4 mg/day, and mycophenolate mofetil (MMF) 2 gr/day, while he also took Vvalcyte and diltiazem. Once diagnosed with KS, the Prograf® (tacrolimus)  was replaced by prednisolone (5 mg/day) and sirolimus (2 mg/day). Gradually the skin nodule on the patient arm disappeared, and the others nodule on the right his leg was decreased. It seems that the examination of skin should be a part of regular follow-up and dermatologist examination is recommended every 6 months.https://acta.tums.ac.ir/index.php/acta/article/view/5156Kaposi’s sarcomaEnd stage renal diseaseKidneyTransplantation
spellingShingle Farzaneh Najafi
Parichehr Kafaie
Hossein Neamatzadeh
Treatment of an Early Kaposi’s Sarcoma Case Post Kidney Transplantation by Sirolimus: A Case Report
Acta Medica Iranica
Kaposi’s sarcoma
End stage renal disease
Kidney
Transplantation
title Treatment of an Early Kaposi’s Sarcoma Case Post Kidney Transplantation by Sirolimus: A Case Report
title_full Treatment of an Early Kaposi’s Sarcoma Case Post Kidney Transplantation by Sirolimus: A Case Report
title_fullStr Treatment of an Early Kaposi’s Sarcoma Case Post Kidney Transplantation by Sirolimus: A Case Report
title_full_unstemmed Treatment of an Early Kaposi’s Sarcoma Case Post Kidney Transplantation by Sirolimus: A Case Report
title_short Treatment of an Early Kaposi’s Sarcoma Case Post Kidney Transplantation by Sirolimus: A Case Report
title_sort treatment of an early kaposi s sarcoma case post kidney transplantation by sirolimus a case report
topic Kaposi’s sarcoma
End stage renal disease
Kidney
Transplantation
url https://acta.tums.ac.ir/index.php/acta/article/view/5156
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AT parichehrkafaie treatmentofanearlykaposissarcomacasepostkidneytransplantationbysirolimusacasereport
AT hosseinneamatzadeh treatmentofanearlykaposissarcomacasepostkidneytransplantationbysirolimusacasereport