Reducing motion sensitivity in 3D high-resolution T2*-weighted MRI by navigator-based motion and nonlinear magnetic field correction
T2*-weighted gradient echo (GRE) MRI at high field is uniquely sensitive to the magnetic properties of tissue and allows the study of brain and vascular anatomy at high spatial resolution. However, it is also sensitive to B0 field changes induced by head motion and physiological processes such as th...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2020-02-01
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| Series: | NeuroImage |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1053811919309231 |
| _version_ | 1818994581496135680 |
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| author | Jiaen Liu Peter van Gelderen Jacco A. de Zwart Jeff H. Duyn |
| author_facet | Jiaen Liu Peter van Gelderen Jacco A. de Zwart Jeff H. Duyn |
| author_sort | Jiaen Liu |
| collection | DOAJ |
| description | T2*-weighted gradient echo (GRE) MRI at high field is uniquely sensitive to the magnetic properties of tissue and allows the study of brain and vascular anatomy at high spatial resolution. However, it is also sensitive to B0 field changes induced by head motion and physiological processes such as the respiratory cycle. Conventional motion correction techniques do not take these field changes into account, and consequently do not fully recover image quality in T2*-weighted MRI. Here, a novel approach was developed to address this by monitoring the B0 field with a volumetric EPI phase navigator. The navigator was acquired at a shorter echo time than that of the (higher resolution) T2*-weighted GRE imaging data and accelerated with parallel imaging for high temporal resolution. At 4 mm isotropic spatial resolution and 0.54 s temporal resolution, the accuracy for estimation of rotation and translation was better than 0.2° and 0.1 mm, respectively. The 10% and 90% percentiles of B0 measurement error using the navigator were −1.8 and 1.5 Hz at 7 T, respectively. A fast retrospective reconstruction algorithm correcting for both motion and nonlinear B0 changes was also developed. The navigator and reconstruction algorithm were evaluated in correcting motion-corrupted high-resolution T2*-weighted GRE MRI on healthy human subjects at 7 T. Excellent image quality was demonstrated with the proposed correction method. |
| first_indexed | 2024-12-20T21:00:14Z |
| format | Article |
| id | doaj.art-9c560ab6f59e43248f87891ae86887b9 |
| institution | Directory Open Access Journal |
| issn | 1095-9572 |
| language | English |
| last_indexed | 2024-12-20T21:00:14Z |
| publishDate | 2020-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | NeuroImage |
| spelling | doaj.art-9c560ab6f59e43248f87891ae86887b92022-12-21T19:26:44ZengElsevierNeuroImage1095-95722020-02-01206116332Reducing motion sensitivity in 3D high-resolution T2*-weighted MRI by navigator-based motion and nonlinear magnetic field correctionJiaen Liu0Peter van Gelderen1Jacco A. de Zwart2Jeff H. Duyn3Corresponding author.; Advanced MRI Section, Laboratory of Functional and Molecular Imaging, National Institute of Neurological Disorders and Stroke, National Institutes of Health, 10 Center Dr. BLDG. 10, RM. B1D-723, Bethesda, MD, 20892-1065, USAAdvanced MRI Section, Laboratory of Functional and Molecular Imaging, National Institute of Neurological Disorders and Stroke, National Institutes of Health, 10 Center Dr. BLDG. 10, RM. B1D-723, Bethesda, MD, 20892-1065, USAAdvanced MRI Section, Laboratory of Functional and Molecular Imaging, National Institute of Neurological Disorders and Stroke, National Institutes of Health, 10 Center Dr. BLDG. 10, RM. B1D-723, Bethesda, MD, 20892-1065, USAAdvanced MRI Section, Laboratory of Functional and Molecular Imaging, National Institute of Neurological Disorders and Stroke, National Institutes of Health, 10 Center Dr. BLDG. 10, RM. B1D-723, Bethesda, MD, 20892-1065, USAT2*-weighted gradient echo (GRE) MRI at high field is uniquely sensitive to the magnetic properties of tissue and allows the study of brain and vascular anatomy at high spatial resolution. However, it is also sensitive to B0 field changes induced by head motion and physiological processes such as the respiratory cycle. Conventional motion correction techniques do not take these field changes into account, and consequently do not fully recover image quality in T2*-weighted MRI. Here, a novel approach was developed to address this by monitoring the B0 field with a volumetric EPI phase navigator. The navigator was acquired at a shorter echo time than that of the (higher resolution) T2*-weighted GRE imaging data and accelerated with parallel imaging for high temporal resolution. At 4 mm isotropic spatial resolution and 0.54 s temporal resolution, the accuracy for estimation of rotation and translation was better than 0.2° and 0.1 mm, respectively. The 10% and 90% percentiles of B0 measurement error using the navigator were −1.8 and 1.5 Hz at 7 T, respectively. A fast retrospective reconstruction algorithm correcting for both motion and nonlinear B0 changes was also developed. The navigator and reconstruction algorithm were evaluated in correcting motion-corrupted high-resolution T2*-weighted GRE MRI on healthy human subjects at 7 T. Excellent image quality was demonstrated with the proposed correction method.http://www.sciencedirect.com/science/article/pii/S1053811919309231T2*-weighted MRIHigh resolutionMotionB0 fieldEPI phase navigator |
| spellingShingle | Jiaen Liu Peter van Gelderen Jacco A. de Zwart Jeff H. Duyn Reducing motion sensitivity in 3D high-resolution T2*-weighted MRI by navigator-based motion and nonlinear magnetic field correction NeuroImage T2*-weighted MRI High resolution Motion B0 field EPI phase navigator |
| title | Reducing motion sensitivity in 3D high-resolution T2*-weighted MRI by navigator-based motion and nonlinear magnetic field correction |
| title_full | Reducing motion sensitivity in 3D high-resolution T2*-weighted MRI by navigator-based motion and nonlinear magnetic field correction |
| title_fullStr | Reducing motion sensitivity in 3D high-resolution T2*-weighted MRI by navigator-based motion and nonlinear magnetic field correction |
| title_full_unstemmed | Reducing motion sensitivity in 3D high-resolution T2*-weighted MRI by navigator-based motion and nonlinear magnetic field correction |
| title_short | Reducing motion sensitivity in 3D high-resolution T2*-weighted MRI by navigator-based motion and nonlinear magnetic field correction |
| title_sort | reducing motion sensitivity in 3d high resolution t2 weighted mri by navigator based motion and nonlinear magnetic field correction |
| topic | T2*-weighted MRI High resolution Motion B0 field EPI phase navigator |
| url | http://www.sciencedirect.com/science/article/pii/S1053811919309231 |
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