Benefits of Implicit Regulation of Instructed Fear: Evidence From Neuroimaging and Functional Connectivity
Instructed fear, which denotes fearful emotions learned from others’ verbal instructions, is an important form of fear acquisition in humans. Maladaptive instructed fear produces detrimental effects on health, but little is known about performing an efficient regulation of instructed fear and its un...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2020-03-01
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| Series: | Frontiers in Neuroscience |
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| Online Access: | https://www.frontiersin.org/article/10.3389/fnins.2020.00201/full |
| _version_ | 1811291767735058432 |
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| author | Yicheng Zhang Yicheng Zhang Shengdong Chen Shengdong Chen Zhongyan Deng Zhongyan Deng Jiemin Yang Jiemin Yang Jiajin Yuan Jiajin Yuan |
| author_facet | Yicheng Zhang Yicheng Zhang Shengdong Chen Shengdong Chen Zhongyan Deng Zhongyan Deng Jiemin Yang Jiemin Yang Jiajin Yuan Jiajin Yuan |
| author_sort | Yicheng Zhang |
| collection | DOAJ |
| description | Instructed fear, which denotes fearful emotions learned from others’ verbal instructions, is an important form of fear acquisition in humans. Maladaptive instructed fear produces detrimental effects on health, but little is known about performing an efficient regulation of instructed fear and its underlying neural substrates. To address this question, 26 subjects performed an instructed fear task where emotional experiences and functional neuroimages were recorded during watching, explicit regulation (calmness imagination), and implicit regulation (calmness priming) conditions. Results indicated that implicit regulation decreased activity in the left amygdala and left insula for instructed fear; however, these effects were absent in explicit regulation. The implementation of implicit regulation did not increase activity in the frontoparietal control regions, while explicit regulation increased dorsolateral prefrontal cortex activity. Furthermore, implicit regulation increased functional connectivity between the right amygdala and right fusiform gyrus, and decreased functional connectivity between the right medial temporal gyrus and left inferior frontal gyrus, which are key nodes of memory retrieval and cognitive control networks, respectively. These findings suggest a favourable effect of implicit regulation on instructed fear, which is subserved by less involvement of control-related brain mechanisms. |
| first_indexed | 2024-04-13T04:35:16Z |
| format | Article |
| id | doaj.art-9c57e8bdcdd74a949444e68c8c535eb9 |
| institution | Directory Open Access Journal |
| issn | 1662-453X |
| language | English |
| last_indexed | 2024-04-13T04:35:16Z |
| publishDate | 2020-03-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neuroscience |
| spelling | doaj.art-9c57e8bdcdd74a949444e68c8c535eb92022-12-22T03:02:12ZengFrontiers Media S.A.Frontiers in Neuroscience1662-453X2020-03-011410.3389/fnins.2020.00201514367Benefits of Implicit Regulation of Instructed Fear: Evidence From Neuroimaging and Functional ConnectivityYicheng Zhang0Yicheng Zhang1Shengdong Chen2Shengdong Chen3Zhongyan Deng4Zhongyan Deng5Jiemin Yang6Jiemin Yang7Jiajin Yuan8Jiajin Yuan9The Laboratory for Affect Cognition and Regulation (ACRLab), Faculty of Psychology, Southwest University, Chongqing, ChinaInstitute of Brain and Psychological Sciences, Sichuan Normal University, Chengdu, ChinaThe Laboratory for Affect Cognition and Regulation (ACRLab), Faculty of Psychology, Southwest University, Chongqing, ChinaInstitute of Brain and Psychological Sciences, Sichuan Normal University, Chengdu, ChinaThe Laboratory for Affect Cognition and Regulation (ACRLab), Faculty of Psychology, Southwest University, Chongqing, ChinaInstitute of Brain and Psychological Sciences, Sichuan Normal University, Chengdu, ChinaThe Laboratory for Affect Cognition and Regulation (ACRLab), Faculty of Psychology, Southwest University, Chongqing, ChinaInstitute of Brain and Psychological Sciences, Sichuan Normal University, Chengdu, ChinaThe Laboratory for Affect Cognition and Regulation (ACRLab), Faculty of Psychology, Southwest University, Chongqing, ChinaInstitute of Brain and Psychological Sciences, Sichuan Normal University, Chengdu, ChinaInstructed fear, which denotes fearful emotions learned from others’ verbal instructions, is an important form of fear acquisition in humans. Maladaptive instructed fear produces detrimental effects on health, but little is known about performing an efficient regulation of instructed fear and its underlying neural substrates. To address this question, 26 subjects performed an instructed fear task where emotional experiences and functional neuroimages were recorded during watching, explicit regulation (calmness imagination), and implicit regulation (calmness priming) conditions. Results indicated that implicit regulation decreased activity in the left amygdala and left insula for instructed fear; however, these effects were absent in explicit regulation. The implementation of implicit regulation did not increase activity in the frontoparietal control regions, while explicit regulation increased dorsolateral prefrontal cortex activity. Furthermore, implicit regulation increased functional connectivity between the right amygdala and right fusiform gyrus, and decreased functional connectivity between the right medial temporal gyrus and left inferior frontal gyrus, which are key nodes of memory retrieval and cognitive control networks, respectively. These findings suggest a favourable effect of implicit regulation on instructed fear, which is subserved by less involvement of control-related brain mechanisms.https://www.frontiersin.org/article/10.3389/fnins.2020.00201/fullimplicit emotion regulationinstructed fearfMRIfunctional connectivityamygdala |
| spellingShingle | Yicheng Zhang Yicheng Zhang Shengdong Chen Shengdong Chen Zhongyan Deng Zhongyan Deng Jiemin Yang Jiemin Yang Jiajin Yuan Jiajin Yuan Benefits of Implicit Regulation of Instructed Fear: Evidence From Neuroimaging and Functional Connectivity Frontiers in Neuroscience implicit emotion regulation instructed fear fMRI functional connectivity amygdala |
| title | Benefits of Implicit Regulation of Instructed Fear: Evidence From Neuroimaging and Functional Connectivity |
| title_full | Benefits of Implicit Regulation of Instructed Fear: Evidence From Neuroimaging and Functional Connectivity |
| title_fullStr | Benefits of Implicit Regulation of Instructed Fear: Evidence From Neuroimaging and Functional Connectivity |
| title_full_unstemmed | Benefits of Implicit Regulation of Instructed Fear: Evidence From Neuroimaging and Functional Connectivity |
| title_short | Benefits of Implicit Regulation of Instructed Fear: Evidence From Neuroimaging and Functional Connectivity |
| title_sort | benefits of implicit regulation of instructed fear evidence from neuroimaging and functional connectivity |
| topic | implicit emotion regulation instructed fear fMRI functional connectivity amygdala |
| url | https://www.frontiersin.org/article/10.3389/fnins.2020.00201/full |
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