Biological effects and toxicity mechanisms of polystyrene nanoplastics: A review
Polystyrene nanoplastics (PS-NPs) are widely used in industry, pharmaceutical and consumer packaging materials, and medical products. The biological health impacts of PS-NPs are receiving increasing attention. Therefore, it is necessary to conduct a literature review of in vitro and in vivo experime...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Editorial Committee of Journal of Environmental and Occupational Medicine
2023-06-01
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| Series: | 环境与职业医学 |
| Subjects: | |
| Online Access: | http://www.jeom.org/article/cn/10.11836/JEOM22447 |
| _version_ | 1797789301355839488 |
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| author | Wenxia BU Xinyuan ZHAO Xiaoke WANG Juan TANG |
| author_facet | Wenxia BU Xinyuan ZHAO Xiaoke WANG Juan TANG |
| author_sort | Wenxia BU |
| collection | DOAJ |
| description | Polystyrene nanoplastics (PS-NPs) are widely used in industry, pharmaceutical and consumer packaging materials, and medical products. The biological health impacts of PS-NPs are receiving increasing attention. Therefore, it is necessary to conduct a literature review of in vitro and in vivo experimental studies from a biological mechanism perspective. Based on the latest research results at home and abroad, this review introduced the characteristics and cell internalization of PS-NPs in cytotoxicity experiments, and summarized the effects of PS-NPs on cytotoxic targets such as mitochondria, lysosomes, proteins, and DNA. In addition, the influencing factors of the health effects of PS-NPs were analyzed from the aspects of physical and chemical properties and cell types. Finally, by discussing the current research hotspots of cytotoxicity mechanism and biological effects, it was anticipated to provide a reference for the health risk management and biological safety assessment of PS-NPs. |
| first_indexed | 2024-03-13T01:48:40Z |
| format | Article |
| id | doaj.art-9c5834d309d749f3836c8231e8aceb3f |
| institution | Directory Open Access Journal |
| issn | 2095-9982 |
| language | English |
| last_indexed | 2024-03-13T01:48:40Z |
| publishDate | 2023-06-01 |
| publisher | Editorial Committee of Journal of Environmental and Occupational Medicine |
| record_format | Article |
| series | 环境与职业医学 |
| spelling | doaj.art-9c5834d309d749f3836c8231e8aceb3f2023-07-03T02:07:30ZengEditorial Committee of Journal of Environmental and Occupational Medicine环境与职业医学2095-99822023-06-0140672873610.11836/JEOM2244722447Biological effects and toxicity mechanisms of polystyrene nanoplastics: A reviewWenxia BU0Xinyuan ZHAO1Xiaoke WANG2Juan TANG3School of Public Health, Nantong University, Nantong, Jiangsu 226019, ChinaSchool of Public Health, Nantong University, Nantong, Jiangsu 226019, ChinaSchool of Public Health, Nantong University, Nantong, Jiangsu 226019, ChinaSchool of Public Health, Nantong University, Nantong, Jiangsu 226019, ChinaPolystyrene nanoplastics (PS-NPs) are widely used in industry, pharmaceutical and consumer packaging materials, and medical products. The biological health impacts of PS-NPs are receiving increasing attention. Therefore, it is necessary to conduct a literature review of in vitro and in vivo experimental studies from a biological mechanism perspective. Based on the latest research results at home and abroad, this review introduced the characteristics and cell internalization of PS-NPs in cytotoxicity experiments, and summarized the effects of PS-NPs on cytotoxic targets such as mitochondria, lysosomes, proteins, and DNA. In addition, the influencing factors of the health effects of PS-NPs were analyzed from the aspects of physical and chemical properties and cell types. Finally, by discussing the current research hotspots of cytotoxicity mechanism and biological effects, it was anticipated to provide a reference for the health risk management and biological safety assessment of PS-NPs.http://www.jeom.org/article/cn/10.11836/JEOM22447polystyrene nanoplasticscytotoxicityoxidative damageautophagylysosome |
| spellingShingle | Wenxia BU Xinyuan ZHAO Xiaoke WANG Juan TANG Biological effects and toxicity mechanisms of polystyrene nanoplastics: A review 环境与职业医学 polystyrene nanoplastics cytotoxicity oxidative damage autophagy lysosome |
| title | Biological effects and toxicity mechanisms of polystyrene nanoplastics: A review |
| title_full | Biological effects and toxicity mechanisms of polystyrene nanoplastics: A review |
| title_fullStr | Biological effects and toxicity mechanisms of polystyrene nanoplastics: A review |
| title_full_unstemmed | Biological effects and toxicity mechanisms of polystyrene nanoplastics: A review |
| title_short | Biological effects and toxicity mechanisms of polystyrene nanoplastics: A review |
| title_sort | biological effects and toxicity mechanisms of polystyrene nanoplastics a review |
| topic | polystyrene nanoplastics cytotoxicity oxidative damage autophagy lysosome |
| url | http://www.jeom.org/article/cn/10.11836/JEOM22447 |
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