Symptoms and subjective quality of life in post-traumatic stress disorder: a longitudinal study.

<h4>Background</h4>Evidence suggests that post-traumatic stress disorder (PTSD) is associated with substantially reduced subjective quality of life (SQOL). This study aimed to explore whether and how changes in the levels of PTSD symptom clusters of intrusion, avoidance and hyperarousal...

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Main Authors: Domenico Giacco, Aleksandra Matanov, Stefan Priebe
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23585868/pdf/?tool=EBI
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author Domenico Giacco
Aleksandra Matanov
Stefan Priebe
author_facet Domenico Giacco
Aleksandra Matanov
Stefan Priebe
author_sort Domenico Giacco
collection DOAJ
description <h4>Background</h4>Evidence suggests that post-traumatic stress disorder (PTSD) is associated with substantially reduced subjective quality of life (SQOL). This study aimed to explore whether and how changes in the levels of PTSD symptom clusters of intrusion, avoidance and hyperarousal are associated with changes in SQOL.<h4>Methods</h4>Two samples with PTSD following the war in former Yugoslavia were studied, i.e. a representative sample of 530 people in five Balkan countries and a non-representative sample of 215 refugees in three Western European countries. They were assessed on average eight years after the war and re-interviewed one year later. PTSD symptoms were assessed on the Impact of Event Scale - Revised and SQOL on the Manchester Short Assessment of Quality of Life. Linear regression and a two-wave cross lagged panel analysis were used to explore the association between PTSD symptom clusters and SQOL.<h4>Results</h4>The findings in the two samples were consistent. Symptom reduction over time was associated with improved SQOL. In multivariable analyses adjusted for the influence of all three clusters, gender and time since war exposure, only changes in hyperarousal symptoms were significantly associated with changes in SQOL. The two-wave cross-lagged panel analysis suggested that the link between hyperarousal symptoms and SQOL is bidirectional.<h4>Conclusions</h4>Low SQOL of patients with war-related PTSD is particularly associated with hyperarousal symptoms. The findings suggest a bidirectional influence: a reduction in hyperarousal symptoms may result in improved SQOL, and improvements in SQOL may lead to reduced hyperarousal symptoms.
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spelling doaj.art-9c59ab45ebb24c9fb8ab029772d841c42022-12-21T23:41:05ZengPublic Library of Science (PLoS)PLoS ONE1932-62032013-01-0184e6099110.1371/journal.pone.0060991Symptoms and subjective quality of life in post-traumatic stress disorder: a longitudinal study.Domenico GiaccoAleksandra MatanovStefan Priebe<h4>Background</h4>Evidence suggests that post-traumatic stress disorder (PTSD) is associated with substantially reduced subjective quality of life (SQOL). This study aimed to explore whether and how changes in the levels of PTSD symptom clusters of intrusion, avoidance and hyperarousal are associated with changes in SQOL.<h4>Methods</h4>Two samples with PTSD following the war in former Yugoslavia were studied, i.e. a representative sample of 530 people in five Balkan countries and a non-representative sample of 215 refugees in three Western European countries. They were assessed on average eight years after the war and re-interviewed one year later. PTSD symptoms were assessed on the Impact of Event Scale - Revised and SQOL on the Manchester Short Assessment of Quality of Life. Linear regression and a two-wave cross lagged panel analysis were used to explore the association between PTSD symptom clusters and SQOL.<h4>Results</h4>The findings in the two samples were consistent. Symptom reduction over time was associated with improved SQOL. In multivariable analyses adjusted for the influence of all three clusters, gender and time since war exposure, only changes in hyperarousal symptoms were significantly associated with changes in SQOL. The two-wave cross-lagged panel analysis suggested that the link between hyperarousal symptoms and SQOL is bidirectional.<h4>Conclusions</h4>Low SQOL of patients with war-related PTSD is particularly associated with hyperarousal symptoms. The findings suggest a bidirectional influence: a reduction in hyperarousal symptoms may result in improved SQOL, and improvements in SQOL may lead to reduced hyperarousal symptoms.https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23585868/pdf/?tool=EBI
spellingShingle Domenico Giacco
Aleksandra Matanov
Stefan Priebe
Symptoms and subjective quality of life in post-traumatic stress disorder: a longitudinal study.
PLoS ONE
title Symptoms and subjective quality of life in post-traumatic stress disorder: a longitudinal study.
title_full Symptoms and subjective quality of life in post-traumatic stress disorder: a longitudinal study.
title_fullStr Symptoms and subjective quality of life in post-traumatic stress disorder: a longitudinal study.
title_full_unstemmed Symptoms and subjective quality of life in post-traumatic stress disorder: a longitudinal study.
title_short Symptoms and subjective quality of life in post-traumatic stress disorder: a longitudinal study.
title_sort symptoms and subjective quality of life in post traumatic stress disorder a longitudinal study
url https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23585868/pdf/?tool=EBI
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AT aleksandramatanov symptomsandsubjectivequalityoflifeinposttraumaticstressdisorderalongitudinalstudy
AT stefanpriebe symptomsandsubjectivequalityoflifeinposttraumaticstressdisorderalongitudinalstudy