Promising Role of the <i>Scutellaria baicalensis</i> Root Hydroxyflavone–Baicalein in the Prevention and Treatment of Human Diseases
Plant roots, due to a high content of natural antioxidants for many years, have been used in herbal medicine. It has been documented that the extract of Baikal skullcap (<i>Scutellaria baicalensis</i>) has hepatoprotective, calming, antiallergic, and anti-inflammatory properties. Flavono...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-03-01
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| Series: | International Journal of Molecular Sciences |
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| Online Access: | https://www.mdpi.com/1422-0067/24/5/4732 |
| _version_ | 1797615177684746240 |
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| author | Marcelina Chmiel Monika Stompor-Gorący |
| author_facet | Marcelina Chmiel Monika Stompor-Gorący |
| author_sort | Marcelina Chmiel |
| collection | DOAJ |
| description | Plant roots, due to a high content of natural antioxidants for many years, have been used in herbal medicine. It has been documented that the extract of Baikal skullcap (<i>Scutellaria baicalensis</i>) has hepatoprotective, calming, antiallergic, and anti-inflammatory properties. Flavonoid compounds found in the extract, including baicalein, have strong antiradical activity, which improves overall health and increases feelings of well-being. Plant-derived bioactive compounds with antioxidant activity have for a long time been used as an alternative source of medicines to treat oxidative stress-related diseases. In this review, we summarized the latest reports on one of the most important aglycones with respect to the pharmacological activity and high content in Baikal skullcap, which is 5,6,7-trihydroxyflavone (baicalein). |
| first_indexed | 2024-03-11T07:22:48Z |
| format | Article |
| id | doaj.art-9c5b000315c044008065ba910835cb0e |
| institution | Directory Open Access Journal |
| issn | 1661-6596 1422-0067 |
| language | English |
| last_indexed | 2024-03-11T07:22:48Z |
| publishDate | 2023-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | International Journal of Molecular Sciences |
| spelling | doaj.art-9c5b000315c044008065ba910835cb0e2023-11-17T07:52:36ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672023-03-01245473210.3390/ijms24054732Promising Role of the <i>Scutellaria baicalensis</i> Root Hydroxyflavone–Baicalein in the Prevention and Treatment of Human DiseasesMarcelina Chmiel0Monika Stompor-Gorący1Department of Human Pathophysiology, Institute of Medical Sciences, University of Rzeszów, Kopisto 2a, 35-315 Rzeszow, PolandDepartment of Human Pathophysiology, Institute of Medical Sciences, University of Rzeszów, Kopisto 2a, 35-315 Rzeszow, PolandPlant roots, due to a high content of natural antioxidants for many years, have been used in herbal medicine. It has been documented that the extract of Baikal skullcap (<i>Scutellaria baicalensis</i>) has hepatoprotective, calming, antiallergic, and anti-inflammatory properties. Flavonoid compounds found in the extract, including baicalein, have strong antiradical activity, which improves overall health and increases feelings of well-being. Plant-derived bioactive compounds with antioxidant activity have for a long time been used as an alternative source of medicines to treat oxidative stress-related diseases. In this review, we summarized the latest reports on one of the most important aglycones with respect to the pharmacological activity and high content in Baikal skullcap, which is 5,6,7-trihydroxyflavone (baicalein).https://www.mdpi.com/1422-0067/24/5/4732root antioxidantsnatural polyphenolsbaicaleinpro-health effect<i>Scutellaria baicalensis</i> |
| spellingShingle | Marcelina Chmiel Monika Stompor-Gorący Promising Role of the <i>Scutellaria baicalensis</i> Root Hydroxyflavone–Baicalein in the Prevention and Treatment of Human Diseases International Journal of Molecular Sciences root antioxidants natural polyphenols baicalein pro-health effect <i>Scutellaria baicalensis</i> |
| title | Promising Role of the <i>Scutellaria baicalensis</i> Root Hydroxyflavone–Baicalein in the Prevention and Treatment of Human Diseases |
| title_full | Promising Role of the <i>Scutellaria baicalensis</i> Root Hydroxyflavone–Baicalein in the Prevention and Treatment of Human Diseases |
| title_fullStr | Promising Role of the <i>Scutellaria baicalensis</i> Root Hydroxyflavone–Baicalein in the Prevention and Treatment of Human Diseases |
| title_full_unstemmed | Promising Role of the <i>Scutellaria baicalensis</i> Root Hydroxyflavone–Baicalein in the Prevention and Treatment of Human Diseases |
| title_short | Promising Role of the <i>Scutellaria baicalensis</i> Root Hydroxyflavone–Baicalein in the Prevention and Treatment of Human Diseases |
| title_sort | promising role of the i scutellaria baicalensis i root hydroxyflavone baicalein in the prevention and treatment of human diseases |
| topic | root antioxidants natural polyphenols baicalein pro-health effect <i>Scutellaria baicalensis</i> |
| url | https://www.mdpi.com/1422-0067/24/5/4732 |
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