Development of Stilbenoid and Chalconoid Analogues as Potent Tyrosinase Modulators and Antioxidant Agents

Development of Stilbenoid and Chalconoid Analogues as Potent Tyrosinase Modulators and Antioxidant Agents

A number of stilbenoid and chalconoid derivatives were prepared by straightforward methods, and their ability to modulate tyrosinase activity and to scavenge free radicals were evaluated in vitro. The cell-free in vitro evaluation revealed two diarylpropanes, <b>24</b> and <b>25<...

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Main Authors: Argyro Vontzalidou, Sapfo-Maria Dimitrakoudi, Konstantinos Tsoukalas, Grigoris Zoidis, Eliza Chaita, Evanthia Dina, Christina Cheimonidi, Ioannis P. Trougakos, George Lambrinidis, Alexios-Leandros Skaltsounis, Emmanuel Mikros, Nektarios Aligiannis
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Antioxidants
Subjects:
tyrosinase inhibition
tyrosinase activation
free-radical-scavenging activity
diarylpropanes
diarylpropenoic acids
dihydrostilbenes
Online Access:https://www.mdpi.com/2076-3921/11/8/1593

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