Cystadenocarcinoma simulating hemangiosarcoma of the salivary gland in dog: case report

Cystadenocarcinoma is regarded as a rare adenocarcinoma variant in animals. This work reports the case of an 8-year-old female Poodle dog with salivary gland cystadenocarcinoma with morphological characteristics similar to a hemangiosarcoma. Histopathological analysis showed a tumor mass with cystic...

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Main Authors: C.O. Gamba, K.A. Damasceno, C.B. Campos, E. Ferreira, G.D. Cassali
Format: Article
Language:English
Published: Universidade Federal de Minas Gerais 2011-06-01
Series:Arquivo Brasileiro de Medicina Veterinária e Zootecnia
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352011000300006&lng=en&tlng=en
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author C.O. Gamba
K.A. Damasceno
C.B. Campos
E. Ferreira
G.D. Cassali
author_facet C.O. Gamba
K.A. Damasceno
C.B. Campos
E. Ferreira
G.D. Cassali
author_sort C.O. Gamba
collection DOAJ
description Cystadenocarcinoma is regarded as a rare adenocarcinoma variant in animals. This work reports the case of an 8-year-old female Poodle dog with salivary gland cystadenocarcinoma with morphological characteristics similar to a hemangiosarcoma. Histopathological analysis showed a tumor mass with cystic formations containing a large amount of red blood cells. In order to distinguish these two entities, periodic acid Schiff (PAS) staining and immunohistochemical analysis were carried out with the use of cytokeratin AE1/AE3 (CK) and CD31-specific antibodies. Neoplastic cells were PAS-negative, CK-positive and CD31-negative confirming their epithelial origin. Based on the findings, the diagnosis of high grade cystadenocarcinoma was established.
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spelling doaj.art-9c5fc8ce4b4d40209a197954bd3042212022-12-22T03:10:26ZengUniversidade Federal de Minas GeraisArquivo Brasileiro de Medicina Veterinária e Zootecnia1678-41622011-06-0163357457810.1590/S0102-09352011000300006S0102-09352011000300006Cystadenocarcinoma simulating hemangiosarcoma of the salivary gland in dog: case reportC.O. Gamba0K.A. Damasceno1C.B. Campos2E. Ferreira3G.D. Cassali4Universidade Federal de Minas GeraisUniversidade Federal de Minas GeraisUniversidade Federal de Minas GeraisUniversidade Federal de Minas GeraisUniversidade Federal de Minas GeraisCystadenocarcinoma is regarded as a rare adenocarcinoma variant in animals. This work reports the case of an 8-year-old female Poodle dog with salivary gland cystadenocarcinoma with morphological characteristics similar to a hemangiosarcoma. Histopathological analysis showed a tumor mass with cystic formations containing a large amount of red blood cells. In order to distinguish these two entities, periodic acid Schiff (PAS) staining and immunohistochemical analysis were carried out with the use of cytokeratin AE1/AE3 (CK) and CD31-specific antibodies. Neoplastic cells were PAS-negative, CK-positive and CD31-negative confirming their epithelial origin. Based on the findings, the diagnosis of high grade cystadenocarcinoma was established.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352011000300006&lng=en&tlng=encadelaglândula salivarCD31células neoplásicas
spellingShingle C.O. Gamba
K.A. Damasceno
C.B. Campos
E. Ferreira
G.D. Cassali
Cystadenocarcinoma simulating hemangiosarcoma of the salivary gland in dog: case report
Arquivo Brasileiro de Medicina Veterinária e Zootecnia
cadela
glândula salivar
CD31
células neoplásicas
title Cystadenocarcinoma simulating hemangiosarcoma of the salivary gland in dog: case report
title_full Cystadenocarcinoma simulating hemangiosarcoma of the salivary gland in dog: case report
title_fullStr Cystadenocarcinoma simulating hemangiosarcoma of the salivary gland in dog: case report
title_full_unstemmed Cystadenocarcinoma simulating hemangiosarcoma of the salivary gland in dog: case report
title_short Cystadenocarcinoma simulating hemangiosarcoma of the salivary gland in dog: case report
title_sort cystadenocarcinoma simulating hemangiosarcoma of the salivary gland in dog case report
topic cadela
glândula salivar
CD31
células neoplásicas
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352011000300006&lng=en&tlng=en
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AT cbcampos cystadenocarcinomasimulatinghemangiosarcomaofthesalivaryglandindogcasereport
AT eferreira cystadenocarcinomasimulatinghemangiosarcomaofthesalivaryglandindogcasereport
AT gdcassali cystadenocarcinomasimulatinghemangiosarcomaofthesalivaryglandindogcasereport