Impact of Type 2 Diabetes Mellitus on Pulmonary Function Tests

Background: Diabetes mellitus is a chronic metabolic disorder that may affect different organs including the lungs. Different studies have been published on the effects of diabetes mellitus on pulmonary function. A restrictive pattern of lung disorder was reported in some studies, whereas an obstru...

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Main Authors: Ruaa Abdulsaid, Azza Sajid, Talib Kadhim Akar
Format: Article
Language:English
Published: College of Pharmacy University of Baghdad 2023-09-01
Series:Iraqi Journal of Pharmaceutical Sciences
Subjects:
Online Access:https://bijps.uobaghdad.edu.iq/index.php/bijps/article/view/1922
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author Ruaa Abdulsaid
Azza Sajid
Talib Kadhim Akar
author_facet Ruaa Abdulsaid
Azza Sajid
Talib Kadhim Akar
author_sort Ruaa Abdulsaid
collection DOAJ
description Background: Diabetes mellitus is a chronic metabolic disorder that may affect different organs including the lungs. Different studies have been published on the effects of diabetes mellitus on pulmonary function. A restrictive pattern of lung disorder was reported in some studies, whereas an obstructive pattern was suggested in others. The study aims to determine the impact of type 2 diabetes on pulmonary function tests (PFTs) and the type of respiratory disorder. Material and Methods: This observational study was conducted in Basrah City, Iraq. One hundred and eighty-two participants were enrolled and divided into 2 groups: 100 healthy (group1) and 82 patients with type2 diabetes mellitus (group 2).PFTs were estimated by a medical spirometer and measurements of several hematological tests were done for each individual. Results: We found a significant decline (p >0.05) in each of FEV1, FVC, PEF, and MVV and a significant increase in ELA in group 2. The restrictive pulmonary disorder was a higher percentage (24.39%) than obstruction (10.9%) and combined (2.43%). Conclusion: Pulmonary function tests were significantly affected by type2 DM and the percentages of different respiratory disorders were higher among group 2 than in group 1, with an increase in restrictive pattern.
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spelling doaj.art-9c62271851cb472da1452fbb0258901e2023-10-01T15:17:49ZengCollege of Pharmacy University of BaghdadIraqi Journal of Pharmaceutical Sciences2521-35121683-35972023-09-0132210.31351/vol32iss2pp25-32Impact of Type 2 Diabetes Mellitus on Pulmonary Function TestsRuaa Abdulsaid 0Azza Sajid1Talib Kadhim Akar 2Ministry of Health and Environments, Basrah Health Directory, Basrah, IraqDepartment of Pharmacology and Toxicology, College of Pharmacy, Basrah University, Basrah, IraqDepartment of Internal Medicine, College of Medicine, University of Basrah, Iraq Background: Diabetes mellitus is a chronic metabolic disorder that may affect different organs including the lungs. Different studies have been published on the effects of diabetes mellitus on pulmonary function. A restrictive pattern of lung disorder was reported in some studies, whereas an obstructive pattern was suggested in others. The study aims to determine the impact of type 2 diabetes on pulmonary function tests (PFTs) and the type of respiratory disorder. Material and Methods: This observational study was conducted in Basrah City, Iraq. One hundred and eighty-two participants were enrolled and divided into 2 groups: 100 healthy (group1) and 82 patients with type2 diabetes mellitus (group 2).PFTs were estimated by a medical spirometer and measurements of several hematological tests were done for each individual. Results: We found a significant decline (p >0.05) in each of FEV1, FVC, PEF, and MVV and a significant increase in ELA in group 2. The restrictive pulmonary disorder was a higher percentage (24.39%) than obstruction (10.9%) and combined (2.43%). Conclusion: Pulmonary function tests were significantly affected by type2 DM and the percentages of different respiratory disorders were higher among group 2 than in group 1, with an increase in restrictive pattern. https://bijps.uobaghdad.edu.iq/index.php/bijps/article/view/1922pulmonary function testsDM2,restrictive pattern
spellingShingle Ruaa Abdulsaid
Azza Sajid
Talib Kadhim Akar
Impact of Type 2 Diabetes Mellitus on Pulmonary Function Tests
Iraqi Journal of Pharmaceutical Sciences
pulmonary function tests
DM2,
restrictive pattern
title Impact of Type 2 Diabetes Mellitus on Pulmonary Function Tests
title_full Impact of Type 2 Diabetes Mellitus on Pulmonary Function Tests
title_fullStr Impact of Type 2 Diabetes Mellitus on Pulmonary Function Tests
title_full_unstemmed Impact of Type 2 Diabetes Mellitus on Pulmonary Function Tests
title_short Impact of Type 2 Diabetes Mellitus on Pulmonary Function Tests
title_sort impact of type 2 diabetes mellitus on pulmonary function tests
topic pulmonary function tests
DM2,
restrictive pattern
url https://bijps.uobaghdad.edu.iq/index.php/bijps/article/view/1922
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