Design, Fabrication, and Testing of a SOI-MEMS-Based Active Microprobe for Potential Cellular Force Sensing Applications
This paper presents the design, analysis, fabrication, and characterization of an electrostatically driven single-axis active probing device for the applications of cellular force sensing and materials characterization. The active microprobe is actuated by linear comb drivers to generate the motion...
Main Authors: | , |
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Format: | Article |
Language: | English |
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SAGE Publishing
2012-01-01
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Series: | Advances in Mechanical Engineering |
Online Access: | https://doi.org/10.1155/2012/785798 |
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author | Li Zhang Jingyan Dong |
author_facet | Li Zhang Jingyan Dong |
author_sort | Li Zhang |
collection | DOAJ |
description | This paper presents the design, analysis, fabrication, and characterization of an electrostatically driven single-axis active probing device for the applications of cellular force sensing and materials characterization. The active microprobe is actuated by linear comb drivers to generate the motion in the probing direction. Both actuation and sensing comb-drive structures are designed for the probing stage. The sensing comb structures enable us to sense the probe displacement when the device is actuated, which enables applications of force-balanced sensing and provides the capability of closed-loop control towards better accuracy. The designed active probing device is fabricated on a silicon-on-insulator (SOI) substrate with a 10 μ m thick device layer through surface micromachining technologies and deep reactive-ion etching (DRIE) process. The handle layer beneath probe stage is etched away by DRIE process to decrease the film damping between the stage and the handle wafer thus achieving high-quality factor. The fabricated stage provides a motion range of 14 μ m at actuation voltage of 140 V. The measured natural frequency of the stage is 1.5 kHz under ambient conditions. A sensitivity of 6 fF/ μ m has been achieved. The proposed single-axis probe is aimed at sensing cellular force which ranges from a few nano-Newton to μ N and micromanipulation applications. |
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id | doaj.art-9c62adf6aba6413183e83bd840fb9774 |
institution | Directory Open Access Journal |
issn | 1687-8132 |
language | English |
last_indexed | 2024-12-11T16:28:51Z |
publishDate | 2012-01-01 |
publisher | SAGE Publishing |
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series | Advances in Mechanical Engineering |
spelling | doaj.art-9c62adf6aba6413183e83bd840fb97742022-12-22T00:58:38ZengSAGE PublishingAdvances in Mechanical Engineering1687-81322012-01-01410.1155/2012/78579810.1155_2012/785798Design, Fabrication, and Testing of a SOI-MEMS-Based Active Microprobe for Potential Cellular Force Sensing ApplicationsLi ZhangJingyan DongThis paper presents the design, analysis, fabrication, and characterization of an electrostatically driven single-axis active probing device for the applications of cellular force sensing and materials characterization. The active microprobe is actuated by linear comb drivers to generate the motion in the probing direction. Both actuation and sensing comb-drive structures are designed for the probing stage. The sensing comb structures enable us to sense the probe displacement when the device is actuated, which enables applications of force-balanced sensing and provides the capability of closed-loop control towards better accuracy. The designed active probing device is fabricated on a silicon-on-insulator (SOI) substrate with a 10 μ m thick device layer through surface micromachining technologies and deep reactive-ion etching (DRIE) process. The handle layer beneath probe stage is etched away by DRIE process to decrease the film damping between the stage and the handle wafer thus achieving high-quality factor. The fabricated stage provides a motion range of 14 μ m at actuation voltage of 140 V. The measured natural frequency of the stage is 1.5 kHz under ambient conditions. A sensitivity of 6 fF/ μ m has been achieved. The proposed single-axis probe is aimed at sensing cellular force which ranges from a few nano-Newton to μ N and micromanipulation applications.https://doi.org/10.1155/2012/785798 |
spellingShingle | Li Zhang Jingyan Dong Design, Fabrication, and Testing of a SOI-MEMS-Based Active Microprobe for Potential Cellular Force Sensing Applications Advances in Mechanical Engineering |
title | Design, Fabrication, and Testing of a SOI-MEMS-Based Active Microprobe for Potential Cellular Force Sensing Applications |
title_full | Design, Fabrication, and Testing of a SOI-MEMS-Based Active Microprobe for Potential Cellular Force Sensing Applications |
title_fullStr | Design, Fabrication, and Testing of a SOI-MEMS-Based Active Microprobe for Potential Cellular Force Sensing Applications |
title_full_unstemmed | Design, Fabrication, and Testing of a SOI-MEMS-Based Active Microprobe for Potential Cellular Force Sensing Applications |
title_short | Design, Fabrication, and Testing of a SOI-MEMS-Based Active Microprobe for Potential Cellular Force Sensing Applications |
title_sort | design fabrication and testing of a soi mems based active microprobe for potential cellular force sensing applications |
url | https://doi.org/10.1155/2012/785798 |
work_keys_str_mv | AT lizhang designfabricationandtestingofasoimemsbasedactivemicroprobeforpotentialcellularforcesensingapplications AT jingyandong designfabricationandtestingofasoimemsbasedactivemicroprobeforpotentialcellularforcesensingapplications |