The Gemstone Cyborg: How Diamond Films Are Creating New Platforms for Cell Regeneration and Biointerfacing
Diamond is a promising material for the biomedical field, mainly due to its set of characteristics such as biocompatibility, strength, and electrical conductivity. Diamond can be synthesised in the laboratory by different methods, is available in the form of plates or films deposited on foreign subs...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-02-01
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| Series: | Molecules |
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| Online Access: | https://www.mdpi.com/1420-3049/28/4/1626 |
| _version_ | 1797619107232743424 |
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| author | Nádia E. Santos Joana C. Mendes Susana Santos Braga |
| author_facet | Nádia E. Santos Joana C. Mendes Susana Santos Braga |
| author_sort | Nádia E. Santos |
| collection | DOAJ |
| description | Diamond is a promising material for the biomedical field, mainly due to its set of characteristics such as biocompatibility, strength, and electrical conductivity. Diamond can be synthesised in the laboratory by different methods, is available in the form of plates or films deposited on foreign substrates, and its morphology varies from microcrystalline diamond to ultrananocrystalline diamond. In this review, we summarise some of the most relevant studies regarding the adhesion of cells onto diamond surfaces, the consequent cell growth, and, in some very interesting cases, the differentiation of cells into neurons and oligodendrocytes. We discuss how different morphologies can affect cell adhesion and how surface termination can influence the surface hydrophilicity and consequent attachment of adherent proteins. At the end of the review, we present a brief perspective on how the results from cell adhesion and biocompatibility can make way for the use of diamond as biointerface. |
| first_indexed | 2024-03-11T08:22:26Z |
| format | Article |
| id | doaj.art-9c63ec9d181e45609d346b13452ac77d |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-03-11T08:22:26Z |
| publishDate | 2023-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-9c63ec9d181e45609d346b13452ac77d2023-11-16T22:21:04ZengMDPI AGMolecules1420-30492023-02-01284162610.3390/molecules28041626The Gemstone Cyborg: How Diamond Films Are Creating New Platforms for Cell Regeneration and BiointerfacingNádia E. Santos0Joana C. Mendes1Susana Santos Braga2LAQV-REQUIMTE, Department of Chemistry, University of Aveiro, 3810-193 Aveiro, PortugalInstituto de Telecomunicações and University of Aveiro, 3810-193 Aveiro, PortugalLAQV-REQUIMTE, Department of Chemistry, University of Aveiro, 3810-193 Aveiro, PortugalDiamond is a promising material for the biomedical field, mainly due to its set of characteristics such as biocompatibility, strength, and electrical conductivity. Diamond can be synthesised in the laboratory by different methods, is available in the form of plates or films deposited on foreign substrates, and its morphology varies from microcrystalline diamond to ultrananocrystalline diamond. In this review, we summarise some of the most relevant studies regarding the adhesion of cells onto diamond surfaces, the consequent cell growth, and, in some very interesting cases, the differentiation of cells into neurons and oligodendrocytes. We discuss how different morphologies can affect cell adhesion and how surface termination can influence the surface hydrophilicity and consequent attachment of adherent proteins. At the end of the review, we present a brief perspective on how the results from cell adhesion and biocompatibility can make way for the use of diamond as biointerface.https://www.mdpi.com/1420-3049/28/4/1626NCDUNCDNSCsneuronscellsadhesion |
| spellingShingle | Nádia E. Santos Joana C. Mendes Susana Santos Braga The Gemstone Cyborg: How Diamond Films Are Creating New Platforms for Cell Regeneration and Biointerfacing Molecules NCD UNCD NSCs neurons cells adhesion |
| title | The Gemstone Cyborg: How Diamond Films Are Creating New Platforms for Cell Regeneration and Biointerfacing |
| title_full | The Gemstone Cyborg: How Diamond Films Are Creating New Platforms for Cell Regeneration and Biointerfacing |
| title_fullStr | The Gemstone Cyborg: How Diamond Films Are Creating New Platforms for Cell Regeneration and Biointerfacing |
| title_full_unstemmed | The Gemstone Cyborg: How Diamond Films Are Creating New Platforms for Cell Regeneration and Biointerfacing |
| title_short | The Gemstone Cyborg: How Diamond Films Are Creating New Platforms for Cell Regeneration and Biointerfacing |
| title_sort | gemstone cyborg how diamond films are creating new platforms for cell regeneration and biointerfacing |
| topic | NCD UNCD NSCs neurons cells adhesion |
| url | https://www.mdpi.com/1420-3049/28/4/1626 |
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