Targeting of immunosuppressive myeloid cells from glioblastoma patients by modulation of size and surface charge of lipid nanocapsules

Targeting of immunosuppressive myeloid cells from glioblastoma patients by modulation of size and surface charge of lipid nanocapsules

Abstract Background Myeloid derived suppressor cells (MDSCs) and tumor-associated macrophages (TAMs) are two of the major players involved in the inhibition of anti-tumor immune response in cancer patients, leading to poor prognosis. Selective targeting of myeloid cells has therefore become an attra...

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Bibliographic Details
Main Authors: Laura Pinton, Sara Magri, Elena Masetto, Marina Vettore, Ilaria Schibuola, Vincenzo Ingangi, Ilaria Marigo, Kevin Matha, Jean-Pierre Benoit, Alessandro Della Puppa, Vincenzo Bronte, Giovanna Lollo, Susanna Mandruzzato
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Journal of Nanobiotechnology
Subjects:
Myeloid cells
Lipid nanocapsules
Glioma
Myeloid derived suppressor cells
Immunosuppression
Online Access:http://link.springer.com/article/10.1186/s12951-020-00589-3

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