Comparison of Ultrasound Descriptors of Abnormally Invasive Placenta (AIP) over the Course of the Second and Third Trimester—Is an Increase Verifiable?
Limited data exist regarding the course of abnormally invasive placentation (AIP) (=placenta accreta spectrum (PAS)) during the 2nd and 3rd trimester, although this knowledge would be important for optimal patient care. In this retrospective single-center longitudinal cohort study, potential aggrava...
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MDPI AG
2021-10-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/10/21/4960 |
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| author | Monika E. Gorczyca Stephanie Springer Petra Pateisky Johannes Ott Barbara Ulm Kinga Chalubinski |
| author_facet | Monika E. Gorczyca Stephanie Springer Petra Pateisky Johannes Ott Barbara Ulm Kinga Chalubinski |
| author_sort | Monika E. Gorczyca |
| collection | DOAJ |
| description | Limited data exist regarding the course of abnormally invasive placentation (AIP) (=placenta accreta spectrum (PAS)) during the 2nd and 3rd trimester, although this knowledge would be important for optimal patient care. In this retrospective single-center longitudinal cohort study, potential aggravation of AIP was evaluated in 37 patients with ultrasound (US) pictures stored on a minimum of two visits. Five raters, blinded to diagnosis and gestational age, judged the degree of AIP as recommended by the International Society for PAS. The probability of invasiveness was estimated as absent, low, intermediate, severe (0–3 points), the extent as absent, focal, diffuse (0–2 points), and the presence and appearance of each US-sign as absent, mild, severe (0–3 points). None of the 10 judged signs appeared more severe (<i>p</i> ≥ 0.41) with progressing pregnancy. Neither the number of positively scored US-signs (earlier scan; 6.14 ± 2.06, later scan; 5.94 ± 2.16; <i>p</i> = 0.28), nor the estimated probability & extent of AIP rose (3.69 ± 1.15 vs. 3.67 ± 1.22; <i>p</i> = 1.0). Test-retest reliability corroborated excellent agreement between visits (mean number of positive US-signs ICC (3,1) = 0.94, 95% CI 0.91–0.97; <i>p</i> < 0.0001). Overall, there was no clinically detectable increase in invasiveness over the course of the 2nd and 3rd trimester. This should be further evaluated in prospective studies. |
| first_indexed | 2024-03-10T05:59:56Z |
| format | Article |
| id | doaj.art-9c674d2d78b948f3ba78e23fdbfe36c6 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-10T05:59:56Z |
| publishDate | 2021-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-9c674d2d78b948f3ba78e23fdbfe36c62023-11-22T21:05:15ZengMDPI AGJournal of Clinical Medicine2077-03832021-10-011021496010.3390/jcm10214960Comparison of Ultrasound Descriptors of Abnormally Invasive Placenta (AIP) over the Course of the Second and Third Trimester—Is an Increase Verifiable?Monika E. Gorczyca0Stephanie Springer1Petra Pateisky2Johannes Ott3Barbara Ulm4Kinga Chalubinski5Department of Obstetrics and Gynecology, Medical University of Vienna, 1090 Vienna, AustriaDepartment of Obstetrics and Gynecology, Medical University of Vienna, 1090 Vienna, AustriaDepartment of Obstetrics and Gynecology, Medical University of Vienna, 1090 Vienna, AustriaDepartment of Obstetrics and Gynecology, Medical University of Vienna, 1090 Vienna, AustriaDepartment of Obstetrics and Gynecology, Medical University of Vienna, 1090 Vienna, AustriaDepartment of Obstetrics and Gynecology, Medical University of Vienna, 1090 Vienna, AustriaLimited data exist regarding the course of abnormally invasive placentation (AIP) (=placenta accreta spectrum (PAS)) during the 2nd and 3rd trimester, although this knowledge would be important for optimal patient care. In this retrospective single-center longitudinal cohort study, potential aggravation of AIP was evaluated in 37 patients with ultrasound (US) pictures stored on a minimum of two visits. Five raters, blinded to diagnosis and gestational age, judged the degree of AIP as recommended by the International Society for PAS. The probability of invasiveness was estimated as absent, low, intermediate, severe (0–3 points), the extent as absent, focal, diffuse (0–2 points), and the presence and appearance of each US-sign as absent, mild, severe (0–3 points). None of the 10 judged signs appeared more severe (<i>p</i> ≥ 0.41) with progressing pregnancy. Neither the number of positively scored US-signs (earlier scan; 6.14 ± 2.06, later scan; 5.94 ± 2.16; <i>p</i> = 0.28), nor the estimated probability & extent of AIP rose (3.69 ± 1.15 vs. 3.67 ± 1.22; <i>p</i> = 1.0). Test-retest reliability corroborated excellent agreement between visits (mean number of positive US-signs ICC (3,1) = 0.94, 95% CI 0.91–0.97; <i>p</i> < 0.0001). Overall, there was no clinically detectable increase in invasiveness over the course of the 2nd and 3rd trimester. This should be further evaluated in prospective studies.https://www.mdpi.com/2077-0383/10/21/4960abnormally invasive placentation (AIP)placenta accreta spectrum (PAS)placentaultrasoundpercretaaccreta |
| spellingShingle | Monika E. Gorczyca Stephanie Springer Petra Pateisky Johannes Ott Barbara Ulm Kinga Chalubinski Comparison of Ultrasound Descriptors of Abnormally Invasive Placenta (AIP) over the Course of the Second and Third Trimester—Is an Increase Verifiable? Journal of Clinical Medicine abnormally invasive placentation (AIP) placenta accreta spectrum (PAS) placenta ultrasound percreta accreta |
| title | Comparison of Ultrasound Descriptors of Abnormally Invasive Placenta (AIP) over the Course of the Second and Third Trimester—Is an Increase Verifiable? |
| title_full | Comparison of Ultrasound Descriptors of Abnormally Invasive Placenta (AIP) over the Course of the Second and Third Trimester—Is an Increase Verifiable? |
| title_fullStr | Comparison of Ultrasound Descriptors of Abnormally Invasive Placenta (AIP) over the Course of the Second and Third Trimester—Is an Increase Verifiable? |
| title_full_unstemmed | Comparison of Ultrasound Descriptors of Abnormally Invasive Placenta (AIP) over the Course of the Second and Third Trimester—Is an Increase Verifiable? |
| title_short | Comparison of Ultrasound Descriptors of Abnormally Invasive Placenta (AIP) over the Course of the Second and Third Trimester—Is an Increase Verifiable? |
| title_sort | comparison of ultrasound descriptors of abnormally invasive placenta aip over the course of the second and third trimester is an increase verifiable |
| topic | abnormally invasive placentation (AIP) placenta accreta spectrum (PAS) placenta ultrasound percreta accreta |
| url | https://www.mdpi.com/2077-0383/10/21/4960 |
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