Nanotechnology; its significance in cancer and photodynamic therapy

In the last decade, developments in nanotechnology have provided a new field in medicine called “Nanomedicine”. Nanomedicine has provided new tools for photodynamic therapy. Quantum dots (QDs) are approximately spherical nanoparticles that have attracted broad attention and have been used in nanomed...

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Main Authors: Mohammad Reza Gaeeni, Morteza Sasani Ghamsari, Marzieh Tohidian, Mohammad Hossein Majles Ara
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2015-07-01
Series:Nanomedicine Journal
Subjects:
Online Access:http://nmj.mums.ac.ir/pdf_4472_10f59779083af1510a913f910ac8659d.html
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author Mohammad Reza Gaeeni
Morteza Sasani Ghamsari
Marzieh Tohidian
Mohammad Hossein Majles Ara
author_facet Mohammad Reza Gaeeni
Morteza Sasani Ghamsari
Marzieh Tohidian
Mohammad Hossein Majles Ara
author_sort Mohammad Reza Gaeeni
collection DOAJ
description In the last decade, developments in nanotechnology have provided a new field in medicine called “Nanomedicine”. Nanomedicine has provided new tools for photodynamic therapy. Quantum dots (QDs) are approximately spherical nanoparticles that have attracted broad attention and have been used in nanomedicine applications. QDs have high molar extinction coefficients and photoluminescence quantum yield, narrow emission spectra, broad absorption, large effective stokes shifts. QDs are more photostable and resistant to metabolic degradation. These photosensitizing properties can be used as photosensitizers for Photodynamic Therapy (PDT). PDT has been recommended for its unique characteristic, such as low side effect and more efficiency. Therefore, nanomedicine leads a promising future for targeted therapy in cancer tumor. Furthermore, QDs have recently been applied in PDT, which will be addressed in this review letter. Also this review letter evaluates key aspects of nano-particulate design and engineering, including the advantage of the nanometer scale size range, biological behavior, and safety profile.
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spelling doaj.art-9c68db049c884a3dbdf10c45ba76ef862022-12-21T18:20:41ZengMashhad University of Medical SciencesNanomedicine Journal2322-30492322-59042015-07-012316717410.7508/nmj.2015.03.0014472Nanotechnology; its significance in cancer and photodynamic therapyMohammad Reza Gaeeni0Morteza Sasani Ghamsari1Marzieh Tohidian2Mohammad Hossein Majles Ara3Photonic Laboratory, Physics Department, Kharazmi University, Tehran, Iran | Laser and Optics Research School, Nuclear Science and Technology Research Institute, North Karegar, Tehran, Iran.Laser and Optics Research School, Nuclear Science and Technology Research Institute, North Karegar, Tehran, IranFaculty of Medicine, Tehran University of Medical Sciences, Tehran, IranPhotonic Laboratory, Physics Department, Kharazmi University, Tehran, IranIn the last decade, developments in nanotechnology have provided a new field in medicine called “Nanomedicine”. Nanomedicine has provided new tools for photodynamic therapy. Quantum dots (QDs) are approximately spherical nanoparticles that have attracted broad attention and have been used in nanomedicine applications. QDs have high molar extinction coefficients and photoluminescence quantum yield, narrow emission spectra, broad absorption, large effective stokes shifts. QDs are more photostable and resistant to metabolic degradation. These photosensitizing properties can be used as photosensitizers for Photodynamic Therapy (PDT). PDT has been recommended for its unique characteristic, such as low side effect and more efficiency. Therefore, nanomedicine leads a promising future for targeted therapy in cancer tumor. Furthermore, QDs have recently been applied in PDT, which will be addressed in this review letter. Also this review letter evaluates key aspects of nano-particulate design and engineering, including the advantage of the nanometer scale size range, biological behavior, and safety profile.http://nmj.mums.ac.ir/pdf_4472_10f59779083af1510a913f910ac8659d.htmlCancer tumorNanomedicinePhotodynamic therapyQuantum dots
spellingShingle Mohammad Reza Gaeeni
Morteza Sasani Ghamsari
Marzieh Tohidian
Mohammad Hossein Majles Ara
Nanotechnology; its significance in cancer and photodynamic therapy
Nanomedicine Journal
Cancer tumor
Nanomedicine
Photodynamic therapy
Quantum dots
title Nanotechnology; its significance in cancer and photodynamic therapy
title_full Nanotechnology; its significance in cancer and photodynamic therapy
title_fullStr Nanotechnology; its significance in cancer and photodynamic therapy
title_full_unstemmed Nanotechnology; its significance in cancer and photodynamic therapy
title_short Nanotechnology; its significance in cancer and photodynamic therapy
title_sort nanotechnology its significance in cancer and photodynamic therapy
topic Cancer tumor
Nanomedicine
Photodynamic therapy
Quantum dots
url http://nmj.mums.ac.ir/pdf_4472_10f59779083af1510a913f910ac8659d.html
work_keys_str_mv AT mohammadrezagaeeni nanotechnologyitssignificanceincancerandphotodynamictherapy
AT mortezasasanighamsari nanotechnologyitssignificanceincancerandphotodynamictherapy
AT marziehtohidian nanotechnologyitssignificanceincancerandphotodynamictherapy
AT mohammadhosseinmajlesara nanotechnologyitssignificanceincancerandphotodynamictherapy