Nanotechnology; its significance in cancer and photodynamic therapy
In the last decade, developments in nanotechnology have provided a new field in medicine called “Nanomedicine”. Nanomedicine has provided new tools for photodynamic therapy. Quantum dots (QDs) are approximately spherical nanoparticles that have attracted broad attention and have been used in nanomed...
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Format: | Article |
Language: | English |
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Mashhad University of Medical Sciences
2015-07-01
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Series: | Nanomedicine Journal |
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Online Access: | http://nmj.mums.ac.ir/pdf_4472_10f59779083af1510a913f910ac8659d.html |
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author | Mohammad Reza Gaeeni Morteza Sasani Ghamsari Marzieh Tohidian Mohammad Hossein Majles Ara |
author_facet | Mohammad Reza Gaeeni Morteza Sasani Ghamsari Marzieh Tohidian Mohammad Hossein Majles Ara |
author_sort | Mohammad Reza Gaeeni |
collection | DOAJ |
description | In the last decade, developments in nanotechnology have provided a new field in medicine called “Nanomedicine”. Nanomedicine has provided new tools for photodynamic therapy. Quantum dots (QDs) are approximately spherical nanoparticles that have attracted broad attention and have been used in nanomedicine applications. QDs have high molar extinction coefficients and photoluminescence quantum yield, narrow emission spectra, broad absorption, large effective stokes shifts. QDs are more photostable and resistant to metabolic degradation. These photosensitizing properties can be used as photosensitizers for Photodynamic Therapy (PDT). PDT has been recommended for its unique characteristic, such as low side effect and more efficiency. Therefore, nanomedicine leads a promising future for targeted therapy in cancer tumor. Furthermore, QDs have recently been applied in PDT, which will be addressed in this review letter. Also this review letter evaluates key aspects of nano-particulate design and engineering, including the advantage of the nanometer scale size range, biological behavior, and safety profile. |
first_indexed | 2024-12-22T16:01:25Z |
format | Article |
id | doaj.art-9c68db049c884a3dbdf10c45ba76ef86 |
institution | Directory Open Access Journal |
issn | 2322-3049 2322-5904 |
language | English |
last_indexed | 2024-12-22T16:01:25Z |
publishDate | 2015-07-01 |
publisher | Mashhad University of Medical Sciences |
record_format | Article |
series | Nanomedicine Journal |
spelling | doaj.art-9c68db049c884a3dbdf10c45ba76ef862022-12-21T18:20:41ZengMashhad University of Medical SciencesNanomedicine Journal2322-30492322-59042015-07-012316717410.7508/nmj.2015.03.0014472Nanotechnology; its significance in cancer and photodynamic therapyMohammad Reza Gaeeni0Morteza Sasani Ghamsari1Marzieh Tohidian2Mohammad Hossein Majles Ara3Photonic Laboratory, Physics Department, Kharazmi University, Tehran, Iran | Laser and Optics Research School, Nuclear Science and Technology Research Institute, North Karegar, Tehran, Iran.Laser and Optics Research School, Nuclear Science and Technology Research Institute, North Karegar, Tehran, IranFaculty of Medicine, Tehran University of Medical Sciences, Tehran, IranPhotonic Laboratory, Physics Department, Kharazmi University, Tehran, IranIn the last decade, developments in nanotechnology have provided a new field in medicine called “Nanomedicine”. Nanomedicine has provided new tools for photodynamic therapy. Quantum dots (QDs) are approximately spherical nanoparticles that have attracted broad attention and have been used in nanomedicine applications. QDs have high molar extinction coefficients and photoluminescence quantum yield, narrow emission spectra, broad absorption, large effective stokes shifts. QDs are more photostable and resistant to metabolic degradation. These photosensitizing properties can be used as photosensitizers for Photodynamic Therapy (PDT). PDT has been recommended for its unique characteristic, such as low side effect and more efficiency. Therefore, nanomedicine leads a promising future for targeted therapy in cancer tumor. Furthermore, QDs have recently been applied in PDT, which will be addressed in this review letter. Also this review letter evaluates key aspects of nano-particulate design and engineering, including the advantage of the nanometer scale size range, biological behavior, and safety profile.http://nmj.mums.ac.ir/pdf_4472_10f59779083af1510a913f910ac8659d.htmlCancer tumorNanomedicinePhotodynamic therapyQuantum dots |
spellingShingle | Mohammad Reza Gaeeni Morteza Sasani Ghamsari Marzieh Tohidian Mohammad Hossein Majles Ara Nanotechnology; its significance in cancer and photodynamic therapy Nanomedicine Journal Cancer tumor Nanomedicine Photodynamic therapy Quantum dots |
title | Nanotechnology; its significance in cancer and photodynamic therapy |
title_full | Nanotechnology; its significance in cancer and photodynamic therapy |
title_fullStr | Nanotechnology; its significance in cancer and photodynamic therapy |
title_full_unstemmed | Nanotechnology; its significance in cancer and photodynamic therapy |
title_short | Nanotechnology; its significance in cancer and photodynamic therapy |
title_sort | nanotechnology its significance in cancer and photodynamic therapy |
topic | Cancer tumor Nanomedicine Photodynamic therapy Quantum dots |
url | http://nmj.mums.ac.ir/pdf_4472_10f59779083af1510a913f910ac8659d.html |
work_keys_str_mv | AT mohammadrezagaeeni nanotechnologyitssignificanceincancerandphotodynamictherapy AT mortezasasanighamsari nanotechnologyitssignificanceincancerandphotodynamictherapy AT marziehtohidian nanotechnologyitssignificanceincancerandphotodynamictherapy AT mohammadhosseinmajlesara nanotechnologyitssignificanceincancerandphotodynamictherapy |