Clinical Factors Associated with COVID-19 Severity in Chronic Hospitalized Infants and Toddlers: Data from a Center in the West Part of Romania
Background: The risk factors for developing a severe form of COVID-19 in young children are poorly understood. Methods: A single-center retrospective study was conducted to quantify and analyze the clinical risk profile of children admitted to the Pediatric Clinic for Nutritional Recovery. Results:...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-04-01
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| Series: | Healthcare |
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| Online Access: | https://www.mdpi.com/2227-9032/10/5/808 |
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| author | Alina Domnicu Mirela Mogoi Aniko Manea Eugen Radu Boia Marioara Boia |
| author_facet | Alina Domnicu Mirela Mogoi Aniko Manea Eugen Radu Boia Marioara Boia |
| author_sort | Alina Domnicu |
| collection | DOAJ |
| description | Background: The risk factors for developing a severe form of COVID-19 in young children are poorly understood. Methods: A single-center retrospective study was conducted to quantify and analyze the clinical risk profile of children admitted to the Pediatric Clinic for Nutritional Recovery. Results: Overall, 51.5% (<i>n</i> = 17) of children were infected with SARS-CoV-2, all symptomatic, and five of them (29.4%) developed a severe form. A positive clinical pulmonary exam was only associated with the severe outcome (OR: 2.00; 95% CI, 0.33–5.66; <i>p</i> = 0.02). Other factors such as age under 3 months, prematurity, birth weight, malnutrition or positive history of congenital cardiac, neurodevelopmental, or genetic diseases, fever, temperature, cough, and digestive symptoms were not found to be significant risk factors. Conclusions: Clinical guidelines based on risk stratification for SARS-CoV-2 infection in children are needed in order to manage, monitor and establish priority access for some groups to high medical care. |
| first_indexed | 2024-03-10T03:48:29Z |
| format | Article |
| id | doaj.art-9c6bde2b3c7e4dba8f9767edfe3d075c |
| institution | Directory Open Access Journal |
| issn | 2227-9032 |
| language | English |
| last_indexed | 2024-03-10T03:48:29Z |
| publishDate | 2022-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Healthcare |
| spelling | doaj.art-9c6bde2b3c7e4dba8f9767edfe3d075c2023-11-23T11:13:21ZengMDPI AGHealthcare2227-90322022-04-0110580810.3390/healthcare10050808Clinical Factors Associated with COVID-19 Severity in Chronic Hospitalized Infants and Toddlers: Data from a Center in the West Part of RomaniaAlina Domnicu0Mirela Mogoi1Aniko Manea2Eugen Radu Boia3Marioara Boia4PhD School Department, “Victor Babes” University of Medicine and Pharmacy Timisoara, Eftimie Murgu Sq., No.2, 300041 Timisoara, RomaniaPediatric Department, “Victor Babes” University of Medicine and Pharmacy Timisoara, Eftimie Murgu Sq., No.2, 300041 Timisoara, RomaniaNeonatology Department, “Victor Babeş” University of Medicine and Pharmacy Timisoara, Eftimie Murgu Sq., No.2, 300041 Timisoara, RomaniaENT Department, “Victor Babes” University of Medicine and Pharmacy Timisoara, Eftimie Murgu Sq., No.2, 300041 Timisoara, RomaniaNeonatology Department, “Victor Babeş” University of Medicine and Pharmacy Timisoara, Eftimie Murgu Sq., No.2, 300041 Timisoara, RomaniaBackground: The risk factors for developing a severe form of COVID-19 in young children are poorly understood. Methods: A single-center retrospective study was conducted to quantify and analyze the clinical risk profile of children admitted to the Pediatric Clinic for Nutritional Recovery. Results: Overall, 51.5% (<i>n</i> = 17) of children were infected with SARS-CoV-2, all symptomatic, and five of them (29.4%) developed a severe form. A positive clinical pulmonary exam was only associated with the severe outcome (OR: 2.00; 95% CI, 0.33–5.66; <i>p</i> = 0.02). Other factors such as age under 3 months, prematurity, birth weight, malnutrition or positive history of congenital cardiac, neurodevelopmental, or genetic diseases, fever, temperature, cough, and digestive symptoms were not found to be significant risk factors. Conclusions: Clinical guidelines based on risk stratification for SARS-CoV-2 infection in children are needed in order to manage, monitor and establish priority access for some groups to high medical care.https://www.mdpi.com/2227-9032/10/5/808COVID-19infanttoddlerrisk factorschronic diseasesmalnutrition |
| spellingShingle | Alina Domnicu Mirela Mogoi Aniko Manea Eugen Radu Boia Marioara Boia Clinical Factors Associated with COVID-19 Severity in Chronic Hospitalized Infants and Toddlers: Data from a Center in the West Part of Romania Healthcare COVID-19 infant toddler risk factors chronic diseases malnutrition |
| title | Clinical Factors Associated with COVID-19 Severity in Chronic Hospitalized Infants and Toddlers: Data from a Center in the West Part of Romania |
| title_full | Clinical Factors Associated with COVID-19 Severity in Chronic Hospitalized Infants and Toddlers: Data from a Center in the West Part of Romania |
| title_fullStr | Clinical Factors Associated with COVID-19 Severity in Chronic Hospitalized Infants and Toddlers: Data from a Center in the West Part of Romania |
| title_full_unstemmed | Clinical Factors Associated with COVID-19 Severity in Chronic Hospitalized Infants and Toddlers: Data from a Center in the West Part of Romania |
| title_short | Clinical Factors Associated with COVID-19 Severity in Chronic Hospitalized Infants and Toddlers: Data from a Center in the West Part of Romania |
| title_sort | clinical factors associated with covid 19 severity in chronic hospitalized infants and toddlers data from a center in the west part of romania |
| topic | COVID-19 infant toddler risk factors chronic diseases malnutrition |
| url | https://www.mdpi.com/2227-9032/10/5/808 |
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