Autophagy-Related Gene WD Repeat Domain 45B Promotes Tumor Proliferation and Migration of Hepatocellular Carcinoma through the Akt/mTOR Signaling Pathway

Autophagy-Related Gene WD Repeat Domain 45B Promotes Tumor Proliferation and Migration of Hepatocellular Carcinoma through the Akt/mTOR Signaling Pathway

Hepatocellular carcinoma (HCC) is a highly aggressive malignant tumor. It has been found that autophagy plays a role both as a tumor promoter and inhibitor in HCC carcinogenesis. However, the mechanism behind is still unveiled. This study aims to explore the functions and mechanism of the key autoph...

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Bibliographic Details
Main Authors: Jiahao Li, Lansi Chen, Jingjing Pang, Chunxiu Yang, Wen Xie, Guoyan Shen, Hongshan Chen, Xiaoyi Li, Shu-Yuan Xiao, Yueying Li
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Diagnostics
Subjects:
hepatocellular carcinoma
autophagy
prognosis
WDR45B
Akt/mTOR signaling pathway
Online Access:https://www.mdpi.com/2075-4418/13/5/906

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