Extracellular Signalling Modulates Scar/WAVE Complex Activity through Abi Phosphorylation

The lamellipodia and pseudopodia of migrating cells are produced and maintained by the Scar/WAVE complex. Thus, actin-based cell migration is largely controlled through regulation of Scar/WAVE. Here, we report that the Abi subunit—but not Scar—is phosphorylated in response to extracellular signallin...

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Bibliographic Details
Main Authors: Shashi Prakash Singh, Peter A. Thomason, Robert H. Insall
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/10/12/3485