Nardosinane-Type Sesquiterpenoids from the Formosan Soft Coral Paralemnalia thyrsoides
Five new nardosinane-type sesquiterpenoids, paralemnolins Q–U (1–5), along with three known compounds (6–8), were isolated from the Formosan soft coral Paralemnalia thyrsoides. The structures of new metabolites were elucidated on the basis of extensive spectroscopic methods, and the absolute configu...
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| Format: | Article |
| Language: | English |
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MDPI AG
2011-09-01
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| Series: | Marine Drugs |
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| Online Access: | http://www.mdpi.com/1660-3397/9/9/1543/ |
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| author | Chi-Hsin Hsu Chang-Feng Dai Jyh-Horng Sheu Bo-Wei Chen Chiung-Yao Huang Jui-Hsin Su Ping-Jyun Sung Zhi-Hong Wen |
| author_facet | Chi-Hsin Hsu Chang-Feng Dai Jyh-Horng Sheu Bo-Wei Chen Chiung-Yao Huang Jui-Hsin Su Ping-Jyun Sung Zhi-Hong Wen |
| author_sort | Chi-Hsin Hsu |
| collection | DOAJ |
| description | Five new nardosinane-type sesquiterpenoids, paralemnolins Q–U (1–5), along with three known compounds (6–8), were isolated from the Formosan soft coral Paralemnalia thyrsoides. The structures of new metabolites were elucidated on the basis of extensive spectroscopic methods, and the absolute configuration of 1 was determined by the application of Mosher’s method on 1. Among these metabolites, 1 and 3 are rarely found nardosinane-type sesquiterpenoids, possessing novel polycyclic structures. Compounds 1, 3, 6 and 7 were found to possess neuroprotective activity. |
| first_indexed | 2024-04-11T21:42:14Z |
| format | Article |
| id | doaj.art-9c6ee0dbcfa04cd5a67d38775bc5fc4a |
| institution | Directory Open Access Journal |
| issn | 1660-3397 |
| language | English |
| last_indexed | 2024-04-11T21:42:14Z |
| publishDate | 2011-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Marine Drugs |
| spelling | doaj.art-9c6ee0dbcfa04cd5a67d38775bc5fc4a2022-12-22T04:01:34ZengMDPI AGMarine Drugs1660-33972011-09-01991543155310.3390/md9091543Nardosinane-Type Sesquiterpenoids from the Formosan Soft Coral Paralemnalia thyrsoidesChi-Hsin HsuChang-Feng DaiJyh-Horng SheuBo-Wei ChenChiung-Yao HuangJui-Hsin SuPing-Jyun SungZhi-Hong WenFive new nardosinane-type sesquiterpenoids, paralemnolins Q–U (1–5), along with three known compounds (6–8), were isolated from the Formosan soft coral Paralemnalia thyrsoides. The structures of new metabolites were elucidated on the basis of extensive spectroscopic methods, and the absolute configuration of 1 was determined by the application of Mosher’s method on 1. Among these metabolites, 1 and 3 are rarely found nardosinane-type sesquiterpenoids, possessing novel polycyclic structures. Compounds 1, 3, 6 and 7 were found to possess neuroprotective activity.http://www.mdpi.com/1660-3397/9/9/1543/soft coralParalemnalia thyrsoidesnardosinaneneuroprotective activity |
| spellingShingle | Chi-Hsin Hsu Chang-Feng Dai Jyh-Horng Sheu Bo-Wei Chen Chiung-Yao Huang Jui-Hsin Su Ping-Jyun Sung Zhi-Hong Wen Nardosinane-Type Sesquiterpenoids from the Formosan Soft Coral Paralemnalia thyrsoides Marine Drugs soft coral Paralemnalia thyrsoides nardosinane neuroprotective activity |
| title | Nardosinane-Type Sesquiterpenoids from the Formosan Soft Coral Paralemnalia thyrsoides |
| title_full | Nardosinane-Type Sesquiterpenoids from the Formosan Soft Coral Paralemnalia thyrsoides |
| title_fullStr | Nardosinane-Type Sesquiterpenoids from the Formosan Soft Coral Paralemnalia thyrsoides |
| title_full_unstemmed | Nardosinane-Type Sesquiterpenoids from the Formosan Soft Coral Paralemnalia thyrsoides |
| title_short | Nardosinane-Type Sesquiterpenoids from the Formosan Soft Coral Paralemnalia thyrsoides |
| title_sort | nardosinane type sesquiterpenoids from the formosan soft coral paralemnalia thyrsoides |
| topic | soft coral Paralemnalia thyrsoides nardosinane neuroprotective activity |
| url | http://www.mdpi.com/1660-3397/9/9/1543/ |
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