A Case of Metastatic Mucoepidermoid Carcinoma Complicated by Resistant Hypercalcemia
Tumors of salivary glands are uncommon and comprise of about 2%–4% of all head and neck tumors. About 75%–80% of these tumors are benign and include pleomorphic adenoma, monomorphic adenoma, oncocytoma, and papillary cystadenoma lymphomatosum. Mucoepidermoid carcinoma is the most common malignant tu...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2011-01-01
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| Series: | Clinical Medicine Insights: Oncology |
| Online Access: | https://doi.org/10.4137/CMO.S5733 |
| _version_ | 1819111246199259136 |
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| author | Muhammad J. Popalzai Nelly Aoun Walid Baz Mervat Mourad Frank Forte Philip Friscia |
| author_facet | Muhammad J. Popalzai Nelly Aoun Walid Baz Mervat Mourad Frank Forte Philip Friscia |
| author_sort | Muhammad J. Popalzai |
| collection | DOAJ |
| description | Tumors of salivary glands are uncommon and comprise of about 2%–4% of all head and neck tumors. About 75%–80% of these tumors are benign and include pleomorphic adenoma, monomorphic adenoma, oncocytoma, and papillary cystadenoma lymphomatosum. Mucoepidermoid carcinoma is the most common malignant tumor of salivary glands, representing 5–10% of all salivary gland tumors. Although known to be metastatic to local lymph nodes, distant metastases are rare (especially, with low and intermediate grade tumors). Histologic grade and the expression of various mucin glycoproteins are useful prognostic indicators. We present a case of mucoepidermoid carcinoma of parotid gland origin with distant metastases which is an uncommon occurrence with intermediate grade tumors. Also, this is the first reported case of humoral hypercalcemia of malignancy secondary to mucoepidermoid carcinoma. |
| first_indexed | 2024-12-22T03:54:34Z |
| format | Article |
| id | doaj.art-9c71c32829194ae9bdace8b443032534 |
| institution | Directory Open Access Journal |
| issn | 1179-5549 |
| language | English |
| last_indexed | 2024-12-22T03:54:34Z |
| publishDate | 2011-01-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Clinical Medicine Insights: Oncology |
| spelling | doaj.art-9c71c32829194ae9bdace8b4430325342022-12-21T18:39:54ZengSAGE PublishingClinical Medicine Insights: Oncology1179-55492011-01-01510.4137/CMO.S5733A Case of Metastatic Mucoepidermoid Carcinoma Complicated by Resistant HypercalcemiaMuhammad J. Popalzai0Nelly Aoun1Walid Baz2Mervat Mourad3Frank Forte4Philip Friscia5Department of Hematology/Oncology, Staten Island University Hospital, Staten Island, NY, 10305, USA.Department of Hematology/Oncology, Staten Island University Hospital, Staten Island, NY, 10305, USA.Department of Hematology/Oncology, Staten Island University Hospital, Staten Island, NY, 10305, USA.Department of Hematology/Oncology, Staten Island University Hospital, Staten Island, NY, 10305, USA.Department of Hematology/Oncology, Staten Island University Hospital, Staten Island, NY, 10305, USA.Department of Hematology/Oncology, Staten Island University Hospital, Staten Island, NY, 10305, USA.Tumors of salivary glands are uncommon and comprise of about 2%–4% of all head and neck tumors. About 75%–80% of these tumors are benign and include pleomorphic adenoma, monomorphic adenoma, oncocytoma, and papillary cystadenoma lymphomatosum. Mucoepidermoid carcinoma is the most common malignant tumor of salivary glands, representing 5–10% of all salivary gland tumors. Although known to be metastatic to local lymph nodes, distant metastases are rare (especially, with low and intermediate grade tumors). Histologic grade and the expression of various mucin glycoproteins are useful prognostic indicators. We present a case of mucoepidermoid carcinoma of parotid gland origin with distant metastases which is an uncommon occurrence with intermediate grade tumors. Also, this is the first reported case of humoral hypercalcemia of malignancy secondary to mucoepidermoid carcinoma.https://doi.org/10.4137/CMO.S5733 |
| spellingShingle | Muhammad J. Popalzai Nelly Aoun Walid Baz Mervat Mourad Frank Forte Philip Friscia A Case of Metastatic Mucoepidermoid Carcinoma Complicated by Resistant Hypercalcemia Clinical Medicine Insights: Oncology |
| title | A Case of Metastatic Mucoepidermoid Carcinoma Complicated by Resistant Hypercalcemia |
| title_full | A Case of Metastatic Mucoepidermoid Carcinoma Complicated by Resistant Hypercalcemia |
| title_fullStr | A Case of Metastatic Mucoepidermoid Carcinoma Complicated by Resistant Hypercalcemia |
| title_full_unstemmed | A Case of Metastatic Mucoepidermoid Carcinoma Complicated by Resistant Hypercalcemia |
| title_short | A Case of Metastatic Mucoepidermoid Carcinoma Complicated by Resistant Hypercalcemia |
| title_sort | case of metastatic mucoepidermoid carcinoma complicated by resistant hypercalcemia |
| url | https://doi.org/10.4137/CMO.S5733 |
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