Genomic and microbial factors affect the prognosis of anti-pd-1 immunotherapy in nasopharyngeal carcinoma

Genomic and microbial factors affect the prognosis of anti-pd-1 immunotherapy in nasopharyngeal carcinoma

Antibodies targeting the programmed cell death protein-1 (PD-1) molecule have been reported to hold promising antitumor activities in patients with nasopharyngeal carcinoma (NPC). However, only a small subset of NPC patients benefits from the anti-PD-1 monotherapy and factors that affect the treatme...

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Bibliographic Details
Main Authors: Liqin Xu, Yuxiang Ma, Chao Fang, Zhuobing Peng, Fangfang Gao, Janne Marie Moll, Shishang Qin, Qichao Yu, Yong Hou, Karsten Kristiansen, Wenfeng Fang, Susanne Brix, Li Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Oncology
Subjects:
NPC
immunotherapy
PD-1
TMB
HLA
EBV
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.953884/full

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