Synthesis and Biological Activities of Luminescent 5,6-Membered Bis(Metallacyclic) Platinum(II) Complexes
Four couples of 5,6-membered bis(metallacyclic) Pt(II) complexes with acetylide and isocyanide auxiliary ligands have been prepared and characterized. The structures of (−)-<b>2</b> and (−)-<b>3</b> are confirmed by single-crystal X-ray diffraction, showing a distorted square...
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MDPI AG
2023-08-01
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| Series: | Molecules |
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| Online Access: | https://www.mdpi.com/1420-3049/28/17/6369 |
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| author | Jing Jing Miao Yu Lei Pan Yang Zhao Guo Xu Hua-Hong Zhang Chen Li Xiao-Peng Zhang |
| author_facet | Jing Jing Miao Yu Lei Pan Yang Zhao Guo Xu Hua-Hong Zhang Chen Li Xiao-Peng Zhang |
| author_sort | Jing Jing |
| collection | DOAJ |
| description | Four couples of 5,6-membered bis(metallacyclic) Pt(II) complexes with acetylide and isocyanide auxiliary ligands have been prepared and characterized. The structures of (−)-<b>2</b> and (−)-<b>3</b> are confirmed by single-crystal X-ray diffraction, showing a distorted square-planar coordination environment around the Pt(II) nucleus. Both solutions and solid samples of all complexes are emissive at RT. Acetylide-coordinated Pt(II) complexes have a lower energy emission than those isocyanide-coordinated ones. The emission spectra of N^N′*C-coordinated Pt(II) derivatives show a lower energy emission maximum relative to N^C*N′-coordinated complexes with the same auxiliary ligand. Moreover, the difference between cyclometalated N^N′*C and N^C*N′ ligands exerts a more remarkable effect on the emission than the auxiliary ligands acetylide and isocyanide. Cytotoxicity and cell imaging of luminescent 5,6-membered bis(metallacyclic) Pt(II) complexes have been evaluated. |
| first_indexed | 2024-03-10T23:16:35Z |
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| id | doaj.art-9c75482c91794c619819820a81cb7ced |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-03-10T23:16:35Z |
| publishDate | 2023-08-01 |
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| series | Molecules |
| spelling | doaj.art-9c75482c91794c619819820a81cb7ced2023-11-19T08:35:01ZengMDPI AGMolecules1420-30492023-08-012817636910.3390/molecules28176369Synthesis and Biological Activities of Luminescent 5,6-Membered Bis(Metallacyclic) Platinum(II) ComplexesJing Jing0Miao Yu1Lei Pan2Yang Zhao3Guo Xu4Hua-Hong Zhang5Chen Li6Xiao-Peng Zhang7Key Laboratory of Water Pollution Treatment & Resource Reuse of Hainan Province, College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou 571158, ChinaKey Laboratory of Water Pollution Treatment & Resource Reuse of Hainan Province, College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou 571158, ChinaKey Laboratory of Water Pollution Treatment & Resource Reuse of Hainan Province, College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou 571158, ChinaKey Laboratory of Water Pollution Treatment & Resource Reuse of Hainan Province, College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou 571158, ChinaKey Laboratory of Water Pollution Treatment & Resource Reuse of Hainan Province, College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou 571158, ChinaKey Laboratory of Water Pollution Treatment & Resource Reuse of Hainan Province, College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou 571158, ChinaKey Laboratory of Water Pollution Treatment & Resource Reuse of Hainan Province, College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou 571158, ChinaKey Laboratory of Water Pollution Treatment & Resource Reuse of Hainan Province, College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou 571158, ChinaFour couples of 5,6-membered bis(metallacyclic) Pt(II) complexes with acetylide and isocyanide auxiliary ligands have been prepared and characterized. The structures of (−)-<b>2</b> and (−)-<b>3</b> are confirmed by single-crystal X-ray diffraction, showing a distorted square-planar coordination environment around the Pt(II) nucleus. Both solutions and solid samples of all complexes are emissive at RT. Acetylide-coordinated Pt(II) complexes have a lower energy emission than those isocyanide-coordinated ones. The emission spectra of N^N′*C-coordinated Pt(II) derivatives show a lower energy emission maximum relative to N^C*N′-coordinated complexes with the same auxiliary ligand. Moreover, the difference between cyclometalated N^N′*C and N^C*N′ ligands exerts a more remarkable effect on the emission than the auxiliary ligands acetylide and isocyanide. Cytotoxicity and cell imaging of luminescent 5,6-membered bis(metallacyclic) Pt(II) complexes have been evaluated.https://www.mdpi.com/1420-3049/28/17/6369platinum(II) complexes5,6-membered bis(metallacycle)biological activitiesemissioncrystal structures |
| spellingShingle | Jing Jing Miao Yu Lei Pan Yang Zhao Guo Xu Hua-Hong Zhang Chen Li Xiao-Peng Zhang Synthesis and Biological Activities of Luminescent 5,6-Membered Bis(Metallacyclic) Platinum(II) Complexes Molecules platinum(II) complexes 5,6-membered bis(metallacycle) biological activities emission crystal structures |
| title | Synthesis and Biological Activities of Luminescent 5,6-Membered Bis(Metallacyclic) Platinum(II) Complexes |
| title_full | Synthesis and Biological Activities of Luminescent 5,6-Membered Bis(Metallacyclic) Platinum(II) Complexes |
| title_fullStr | Synthesis and Biological Activities of Luminescent 5,6-Membered Bis(Metallacyclic) Platinum(II) Complexes |
| title_full_unstemmed | Synthesis and Biological Activities of Luminescent 5,6-Membered Bis(Metallacyclic) Platinum(II) Complexes |
| title_short | Synthesis and Biological Activities of Luminescent 5,6-Membered Bis(Metallacyclic) Platinum(II) Complexes |
| title_sort | synthesis and biological activities of luminescent 5 6 membered bis metallacyclic platinum ii complexes |
| topic | platinum(II) complexes 5,6-membered bis(metallacycle) biological activities emission crystal structures |
| url | https://www.mdpi.com/1420-3049/28/17/6369 |
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