Plasminogen mediates communication between the peripheral and central immune systems during systemic immune challenge with lipopolysaccharide
Abstract Background Systemic inflammation has been implicated in the progression of many neurodegenerative diseases and may be an important driver of the disease. Dementia and cognitive decline progress more rapidly following acute systemic infection, and systemic inflammation midlife is predictive...
Main Authors: | Sarah K. Baker, Zu-Lin Chen, Erin H. Norris, Sidney Strickland |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-08-01
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Series: | Journal of Neuroinflammation |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12974-019-1560-y |
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