Large bilateral foveal cysts in the inner retina of a patient treated with tamoxifen, diagnosed with Fourier-domain optical coherence tomography

Ilias Georgalas, Theodore Paraskevopoulos, Dimitris Papaconstaninou, Dimitiris Brouzas, Chryssanthi Koutsandrea Department of Ophthalmology, "G Gennimatas" Hospital of Athens, NHS, University of Athens, Athens, Greece Purpose: To report a case of a patient receiving tamoxifen with visual d...

Full description

Bibliographic Details
Main Authors: Georgalas I, Paraskevopoulos T, Papaconstantinou D, Brouzas D, Koutsandrea C
Format: Article
Language:English
Published: Dove Medical Press 2013-04-01
Series:Clinical Ophthalmology
Online Access:http://www.dovepress.com/large-bilateral-foveal-cysts-in-the-inner-retina-of-a-patient-treated--a12714
_version_ 1818421092041097216
author Georgalas I
Paraskevopoulos T
Papaconstantinou D
Brouzas D
Koutsandrea C
author_facet Georgalas I
Paraskevopoulos T
Papaconstantinou D
Brouzas D
Koutsandrea C
author_sort Georgalas I
collection DOAJ
description Ilias Georgalas, Theodore Paraskevopoulos, Dimitris Papaconstaninou, Dimitiris Brouzas, Chryssanthi Koutsandrea Department of Ophthalmology, "G Gennimatas" Hospital of Athens, NHS, University of Athens, Athens, Greece Purpose: To report a case of a patient receiving tamoxifen with visual deterioration and describe the unusual optical coherence tomography (OCT) findings. Method: Observational case report. Results: A 55-year-old female patient was referred to our department complaining of gradual visual deterioration in both eyes. Medical history was unremarkable apart from breast cancer for which she had received tamoxifen for 10 years (mean dosage 20 mg/day). Best corrected visual acuity was 20/400 in her right eye and 20/40 in her left eye. Fundoscopy in both eyes was without any obvious signs of maculopathy. However, Fourier-domain OCT demonstrated bilateral extensive areas of disruption in inner retinal layers without any signs of crystalline retinopathy. Six months after the cessation of tamoxifen, the situation remains unchanged. Conclusion: Patients receiving tamoxifen should be monitored with high-resolution OCT for fundoscopically invisible changes in the inner retinal layers, the progression of which may seriously affect the patient's vision and subsequently their quality of life. Keywords: maculopathy, OCT
first_indexed 2024-12-14T13:04:51Z
format Article
id doaj.art-9c7b122e821e4f94bef1b4dd842aedd4
institution Directory Open Access Journal
issn 1177-5467
1177-5483
language English
last_indexed 2024-12-14T13:04:51Z
publishDate 2013-04-01
publisher Dove Medical Press
record_format Article
series Clinical Ophthalmology
spelling doaj.art-9c7b122e821e4f94bef1b4dd842aedd42022-12-21T23:00:20ZengDove Medical PressClinical Ophthalmology1177-54671177-54832013-04-012013default707709Large bilateral foveal cysts in the inner retina of a patient treated with tamoxifen, diagnosed with Fourier-domain optical coherence tomographyGeorgalas IParaskevopoulos TPapaconstantinou DBrouzas DKoutsandrea CIlias Georgalas, Theodore Paraskevopoulos, Dimitris Papaconstaninou, Dimitiris Brouzas, Chryssanthi Koutsandrea Department of Ophthalmology, "G Gennimatas" Hospital of Athens, NHS, University of Athens, Athens, Greece Purpose: To report a case of a patient receiving tamoxifen with visual deterioration and describe the unusual optical coherence tomography (OCT) findings. Method: Observational case report. Results: A 55-year-old female patient was referred to our department complaining of gradual visual deterioration in both eyes. Medical history was unremarkable apart from breast cancer for which she had received tamoxifen for 10 years (mean dosage 20 mg/day). Best corrected visual acuity was 20/400 in her right eye and 20/40 in her left eye. Fundoscopy in both eyes was without any obvious signs of maculopathy. However, Fourier-domain OCT demonstrated bilateral extensive areas of disruption in inner retinal layers without any signs of crystalline retinopathy. Six months after the cessation of tamoxifen, the situation remains unchanged. Conclusion: Patients receiving tamoxifen should be monitored with high-resolution OCT for fundoscopically invisible changes in the inner retinal layers, the progression of which may seriously affect the patient's vision and subsequently their quality of life. Keywords: maculopathy, OCThttp://www.dovepress.com/large-bilateral-foveal-cysts-in-the-inner-retina-of-a-patient-treated--a12714
spellingShingle Georgalas I
Paraskevopoulos T
Papaconstantinou D
Brouzas D
Koutsandrea C
Large bilateral foveal cysts in the inner retina of a patient treated with tamoxifen, diagnosed with Fourier-domain optical coherence tomography
Clinical Ophthalmology
title Large bilateral foveal cysts in the inner retina of a patient treated with tamoxifen, diagnosed with Fourier-domain optical coherence tomography
title_full Large bilateral foveal cysts in the inner retina of a patient treated with tamoxifen, diagnosed with Fourier-domain optical coherence tomography
title_fullStr Large bilateral foveal cysts in the inner retina of a patient treated with tamoxifen, diagnosed with Fourier-domain optical coherence tomography
title_full_unstemmed Large bilateral foveal cysts in the inner retina of a patient treated with tamoxifen, diagnosed with Fourier-domain optical coherence tomography
title_short Large bilateral foveal cysts in the inner retina of a patient treated with tamoxifen, diagnosed with Fourier-domain optical coherence tomography
title_sort large bilateral foveal cysts in the inner retina of a patient treated with tamoxifen diagnosed with fourier domain optical coherence tomography
url http://www.dovepress.com/large-bilateral-foveal-cysts-in-the-inner-retina-of-a-patient-treated--a12714
work_keys_str_mv AT georgalasi largebilateralfovealcystsintheinnerretinaofapatienttreatedwithtamoxifendiagnosedwithfourierdomainopticalcoherencetomography
AT paraskevopoulost largebilateralfovealcystsintheinnerretinaofapatienttreatedwithtamoxifendiagnosedwithfourierdomainopticalcoherencetomography
AT papaconstantinoud largebilateralfovealcystsintheinnerretinaofapatienttreatedwithtamoxifendiagnosedwithfourierdomainopticalcoherencetomography
AT brouzasd largebilateralfovealcystsintheinnerretinaofapatienttreatedwithtamoxifendiagnosedwithfourierdomainopticalcoherencetomography
AT koutsandreac largebilateralfovealcystsintheinnerretinaofapatienttreatedwithtamoxifendiagnosedwithfourierdomainopticalcoherencetomography