Polymorphism of apolipoprotein A1 gene and lipid profile of blood serum in the Evenki and Buryat populations
The prevalence of genotypes and alleles of polymorphic markers (-75)G>A and (+83)C>T apolipoprotein A1 gene (ApOAl) in samples of ethnic groups from Eastern Siberia (the Evenkis and Buryats) were studied. In the Evenki population allele (-75)A was registered in 22,7 % cases, in the Buryat popu...
| Main Authors: | , , , , , |
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| 格式: | 文件 |
| 语言: | Russian |
| 出版: |
Scientific Сentre for Family Health and Human Reproduction Problems
2015-05-01
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| 丛编: | Acta Biomedica Scientifica |
| 主题: | |
| 在线阅读: | https://www.actabiomedica.ru/jour/article/view/75 |
| 总结: | The prevalence of genotypes and alleles of polymorphic markers (-75)G>A and (+83)C>T apolipoprotein A1 gene (ApOAl) in samples of ethnic groups from Eastern Siberia (the Evenkis and Buryats) were studied. In the Evenki population allele (-75)A was registered in 22,7 % cases, in the Buryat population - in 22,4 % cases. In the Evenki population allele (+83)T was found in 6,3 % cases, in the Buryat population - in 5,9 % cases. Statistically significant differences of genotypes and alleles APOA1 prevalence between the Evenkis and the Buryats was not found. The prevalence of alleles (-75)G>A and (+83)C>T of gene APOA1 obtained in the study were compared with the prevalence in different populations around the world. For each teenager in the study group we conducted a biochemical analysis of serum lipid profile. Also a comparative analysis of blood lipid profile in carriers of different genotypes was carried out. Comparative analysis of blood lipid profile in carriers of different genotypes was conducted. |
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| ISSN: | 2541-9420 2587-9596 |