Lack of Ecto-5′-Nucleotidase Protects Sensitized Mice against Allergen Challenge

Lack of Ecto-5′-Nucleotidase Protects Sensitized Mice against Allergen Challenge

Ecto-5′-nucleotidase (CD73), the ectoenzyme that together with CD39 is responsible for extracellular ATP hydrolysis and adenosine accumulation, regulates immune/inflammatory processes by controlling innate and acquired immunity cell functions. We previously demonstrated that CD73 is required for the...

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Bibliographic Details
Main Authors: Elisabetta Caiazzo, Ida Cerqua, Roberta Turiello, Maria Antonietta Riemma, Giacomo De Palma, Armando Ialenti, Fiorentina Roviezzo, Silvana Morello, Carla Cicala
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Biomolecules
Subjects:
airways
allergy
CD73
ecto-5′-nucleotidase
mast cells
hyperresponsiveness
Online Access:https://www.mdpi.com/2218-273X/12/5/697

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