COMPARISON EFFECT BETWEEN PEGAGAN (Centella asiatica) EXTRACT AND PRAMIPEXOLE TOWARD LOCOMOTOR ACTIVITIES, α - SYNUCLEIN, AND NRF2 EXPRESSION IN ZEBRAFISH PARKINSON MODEL

COMPARISON EFFECT BETWEEN PEGAGAN (Centella asiatica) EXTRACT AND PRAMIPEXOLE TOWARD LOCOMOTOR ACTIVITIES, α - SYNUCLEIN, AND NRF2 EXPRESSION IN ZEBRAFISH PARKINSON MODEL

Background: Parkinson disease is characterized with deposition of Lewy Bodies containing α–synuclein happened due to the effect of chronic neuroinflammation that causes the death of dopaminergic neurons through oxidative stress processes, so it involves the response of Nuclear factor erythroid 2-lik...

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Bibliographic Details
Main Authors: Ayu Trisnawati, Anasrulloh Anasrulloh, Sri Budhi Rianawati, Husnul Khotimah, Mulyohadi Ali, Budi Susetya
Format: Article
Language:English
Published: University of Brawijaya 2019-01-01
Series:Malang Neurology Journal
Subjects:
centella asiatica
locomotor activity
α–synuclein
nrf2
parkinson disease
zebrafish
Online Access:https://mnj.ub.ac.id/index.php/mnj/article/view/291

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