Seroprevalence of Anti-HCV Antibody in Patients with Chronic Kidney Disease before Starting Dialysis Therapy
Background: Hepatitis C virus (HCV) infection and chronic kidney disease are common and potentially serious medical problems throughout the world. In recent years, it has become clear that these two conditions are linked in several important ways. Indeed, some forms of renal diseases are precipitate...
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| Format: | Article |
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Enam Medical College, Dhaka
2017-01-01
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| Series: | Journal of Enam Medical College |
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| Online Access: | http://www.banglajol.info/index.php/JEMC/article/view/30746 |
| _version_ | 1818362622955749376 |
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| author | Fareha Jesmin Rabbi Kaniz Fatema Md Morshed Alam |
| author_facet | Fareha Jesmin Rabbi Kaniz Fatema Md Morshed Alam |
| author_sort | Fareha Jesmin Rabbi |
| collection | DOAJ |
| description | Background: Hepatitis C virus (HCV) infection and chronic kidney disease are common and potentially serious medical problems throughout the world. In recent years, it has become clear that these two conditions are linked in several important ways. Indeed, some forms of renal diseases are precipitated by HCV infection and patients with end-stage renal disease (ESRD) are at increased risk for acquiring HCV infection. Patients with chronic kidney disease typically show an impaired immune response compared with healthy individuals and also other risk factors related with treatment and management. CKD patients ultimately undergo end stage renal therapy like dialysis for their treatment and survival. Risk factors for the infections are more in dialysis period than in predialytic stages. Like other developing countries CKD patients with HCV infection are very common in our country. For this reason the CKD patients should be properly diagnosed knowing the infection status before dialysis which would help both the patient and doctor to choose their proper treatment approach.
Objective: This cross-sectional study was done to know the prevalence of HCV infection in the CKD patients before starting dialysis therapy.
Materials and Methods: A total of 197 patients with chronic kidney disease stage five (CKD-V) before starting dialysis therapy were included as subjects of this study. Among the CKD patients anti-HCV was detected to see prevalence of hepatitis C virus infection. The patients were also tested for HBsAg to assess co-infection. After collecting all the data of different test results analyses were done by SPSS version 15.0.
Results: In this study 195 (99%) patients were anti-HCV negative and only two patients (1%) were found positive.
Conclusion: HCV infection in CKD patients before dialysis should be taken into account so that HCV negative CKD patients would not get the infection during dialysis and standard screening procedures should be taken to prevent transmission of infection. |
| first_indexed | 2024-12-13T21:35:31Z |
| format | Article |
| id | doaj.art-9c86397c9e094b40869b69adf1d1ae8a |
| institution | Directory Open Access Journal |
| issn | 2227-6688 2304-9316 |
| language | English |
| last_indexed | 2024-12-13T21:35:31Z |
| publishDate | 2017-01-01 |
| publisher | Enam Medical College, Dhaka |
| record_format | Article |
| series | Journal of Enam Medical College |
| spelling | doaj.art-9c86397c9e094b40869b69adf1d1ae8a2022-12-21T23:30:41ZengEnam Medical College, DhakaJournal of Enam Medical College2227-66882304-93162017-01-0171202410.3329/jemc.v7i1.30746Seroprevalence of Anti-HCV Antibody in Patients with Chronic Kidney Disease before Starting Dialysis TherapyFareha Jesmin Rabbi0Kaniz Fatema1Md Morshed Alam2Associate Professor, Department of Clinical Immunology, National Institute of Kidney Diseases and Urology (NIKDU), Dhaka, BangladeshAssistant Professor, Department of Clinical Immunology, National Institute of Kidney Diseases and Urology, Dhaka, Bangladesh Assistant Professor, Department of Biochemistry, National Institute of Kidney Diseases and Urology, Dhaka, Bangladesh Background: Hepatitis C virus (HCV) infection and chronic kidney disease are common and potentially serious medical problems throughout the world. In recent years, it has become clear that these two conditions are linked in several important ways. Indeed, some forms of renal diseases are precipitated by HCV infection and patients with end-stage renal disease (ESRD) are at increased risk for acquiring HCV infection. Patients with chronic kidney disease typically show an impaired immune response compared with healthy individuals and also other risk factors related with treatment and management. CKD patients ultimately undergo end stage renal therapy like dialysis for their treatment and survival. Risk factors for the infections are more in dialysis period than in predialytic stages. Like other developing countries CKD patients with HCV infection are very common in our country. For this reason the CKD patients should be properly diagnosed knowing the infection status before dialysis which would help both the patient and doctor to choose their proper treatment approach. Objective: This cross-sectional study was done to know the prevalence of HCV infection in the CKD patients before starting dialysis therapy. Materials and Methods: A total of 197 patients with chronic kidney disease stage five (CKD-V) before starting dialysis therapy were included as subjects of this study. Among the CKD patients anti-HCV was detected to see prevalence of hepatitis C virus infection. The patients were also tested for HBsAg to assess co-infection. After collecting all the data of different test results analyses were done by SPSS version 15.0. Results: In this study 195 (99%) patients were anti-HCV negative and only two patients (1%) were found positive. Conclusion: HCV infection in CKD patients before dialysis should be taken into account so that HCV negative CKD patients would not get the infection during dialysis and standard screening procedures should be taken to prevent transmission of infection.http://www.banglajol.info/index.php/JEMC/article/view/30746Chronic kidney disease; HCV infection; Dialysis |
| spellingShingle | Fareha Jesmin Rabbi Kaniz Fatema Md Morshed Alam Seroprevalence of Anti-HCV Antibody in Patients with Chronic Kidney Disease before Starting Dialysis Therapy Journal of Enam Medical College Chronic kidney disease; HCV infection; Dialysis |
| title | Seroprevalence of Anti-HCV Antibody in Patients with Chronic Kidney Disease before Starting Dialysis Therapy |
| title_full | Seroprevalence of Anti-HCV Antibody in Patients with Chronic Kidney Disease before Starting Dialysis Therapy |
| title_fullStr | Seroprevalence of Anti-HCV Antibody in Patients with Chronic Kidney Disease before Starting Dialysis Therapy |
| title_full_unstemmed | Seroprevalence of Anti-HCV Antibody in Patients with Chronic Kidney Disease before Starting Dialysis Therapy |
| title_short | Seroprevalence of Anti-HCV Antibody in Patients with Chronic Kidney Disease before Starting Dialysis Therapy |
| title_sort | seroprevalence of anti hcv antibody in patients with chronic kidney disease before starting dialysis therapy |
| topic | Chronic kidney disease; HCV infection; Dialysis |
| url | http://www.banglajol.info/index.php/JEMC/article/view/30746 |
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