Underdiagnosis of Foodborne Hepatitis A, the Netherlands, 2008–2010
Outbreaks of foodborne hepatitis A are rarely recognized as such. Detection of these infections is challenging because of the infection’s long incubation period and patients’ recall bias. Nevertheless, the complex food market might lead to reemergence of hepatitis A virus outside of disease-endemic...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Centers for Disease Control and Prevention
2014-04-01
|
| Series: | Emerging Infectious Diseases |
| Subjects: | |
| Online Access: | https://wwwnc.cdc.gov/eid/article/20/4/13-0753_article |
| _version_ | 1811263398359334912 |
|---|---|
| author | Mariska Petrignani Linda Verhoef Harry Vennema Rianne van Hunen Dominique Baas Jim E. van Steenbergen Marion P.G. Koopmans |
| author_facet | Mariska Petrignani Linda Verhoef Harry Vennema Rianne van Hunen Dominique Baas Jim E. van Steenbergen Marion P.G. Koopmans |
| author_sort | Mariska Petrignani |
| collection | DOAJ |
| description | Outbreaks of foodborne hepatitis A are rarely recognized as such. Detection of these infections is challenging because of the infection’s long incubation period and patients’ recall bias. Nevertheless, the complex food market might lead to reemergence of hepatitis A virus outside of disease-endemic areas. To assess the role of food as a source of infection, we combined routine surveillance with real-time strain sequencing in the Netherlands during 2008–2010. Virus RNA from serum of 248 (59%) of 421 reported case-patients could be sequenced. Without typing, foodborne transmission was suspected for only 4% of reported case-patients. With typing, foodborne transmission increased to being the most probable source of infection for 16%. We recommend routine implementation of an enhanced surveillance system that includes prompt forwarding and typing of hepatitis A virus RNA isolated from serum, standard use of questionnaires, data sharing, and centralized interpretation of data. |
| first_indexed | 2024-04-12T19:43:20Z |
| format | Article |
| id | doaj.art-9c8644eda8f94dfe8b87e254c29f6f87 |
| institution | Directory Open Access Journal |
| issn | 1080-6040 1080-6059 |
| language | English |
| last_indexed | 2024-04-12T19:43:20Z |
| publishDate | 2014-04-01 |
| publisher | Centers for Disease Control and Prevention |
| record_format | Article |
| series | Emerging Infectious Diseases |
| spelling | doaj.art-9c8644eda8f94dfe8b87e254c29f6f872022-12-22T03:19:01ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592014-04-0120459660210.3201/eid2004.130753Underdiagnosis of Foodborne Hepatitis A, the Netherlands, 2008–2010Mariska PetrignaniLinda VerhoefHarry VennemaRianne van HunenDominique BaasJim E. van SteenbergenMarion P.G. KoopmansOutbreaks of foodborne hepatitis A are rarely recognized as such. Detection of these infections is challenging because of the infection’s long incubation period and patients’ recall bias. Nevertheless, the complex food market might lead to reemergence of hepatitis A virus outside of disease-endemic areas. To assess the role of food as a source of infection, we combined routine surveillance with real-time strain sequencing in the Netherlands during 2008–2010. Virus RNA from serum of 248 (59%) of 421 reported case-patients could be sequenced. Without typing, foodborne transmission was suspected for only 4% of reported case-patients. With typing, foodborne transmission increased to being the most probable source of infection for 16%. We recommend routine implementation of an enhanced surveillance system that includes prompt forwarding and typing of hepatitis A virus RNA isolated from serum, standard use of questionnaires, data sharing, and centralized interpretation of data.https://wwwnc.cdc.gov/eid/article/20/4/13-0753_articlefoodborne diseaseshepatitis A virusepidemiologymolecular typingpublic healththe Netherlands |
| spellingShingle | Mariska Petrignani Linda Verhoef Harry Vennema Rianne van Hunen Dominique Baas Jim E. van Steenbergen Marion P.G. Koopmans Underdiagnosis of Foodborne Hepatitis A, the Netherlands, 2008–2010 Emerging Infectious Diseases foodborne diseases hepatitis A virus epidemiology molecular typing public health the Netherlands |
| title | Underdiagnosis of Foodborne Hepatitis A, the Netherlands, 2008–2010 |
| title_full | Underdiagnosis of Foodborne Hepatitis A, the Netherlands, 2008–2010 |
| title_fullStr | Underdiagnosis of Foodborne Hepatitis A, the Netherlands, 2008–2010 |
| title_full_unstemmed | Underdiagnosis of Foodborne Hepatitis A, the Netherlands, 2008–2010 |
| title_short | Underdiagnosis of Foodborne Hepatitis A, the Netherlands, 2008–2010 |
| title_sort | underdiagnosis of foodborne hepatitis a the netherlands 2008 2010 |
| topic | foodborne diseases hepatitis A virus epidemiology molecular typing public health the Netherlands |
| url | https://wwwnc.cdc.gov/eid/article/20/4/13-0753_article |
| work_keys_str_mv | AT mariskapetrignani underdiagnosisoffoodbornehepatitisathenetherlands20082010 AT lindaverhoef underdiagnosisoffoodbornehepatitisathenetherlands20082010 AT harryvennema underdiagnosisoffoodbornehepatitisathenetherlands20082010 AT riannevanhunen underdiagnosisoffoodbornehepatitisathenetherlands20082010 AT dominiquebaas underdiagnosisoffoodbornehepatitisathenetherlands20082010 AT jimevansteenbergen underdiagnosisoffoodbornehepatitisathenetherlands20082010 AT marionpgkoopmans underdiagnosisoffoodbornehepatitisathenetherlands20082010 |