Resistance of Omicron subvariants BA.2.75.2, BA.4.6, and BQ.1.1 to neutralizing antibodies
In this work, Planas et al. report that Omicron subvariants BA.2.75.2, BA.4.6, and BQ.1.1 escape neutralization from monoclonal antibodies, and sera from vaccinated individuals with or without Omicron BA.1/2 or BA.5 breakthrough infection.
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2023-02-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-023-36561-6 |
| _version_ | 1797864185114132480 |
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| author | Delphine Planas Timothée Bruel Isabelle Staropoli Florence Guivel-Benhassine Françoise Porrot Piet Maes Ludivine Grzelak Matthieu Prot Said Mougari Cyril Planchais Julien Puech Madelina Saliba Riwan Sahraoui Florent Fémy Nathalie Morel Jérémy Dufloo Rafael Sanjuán Hugo Mouquet Emmanuel André Laurent Hocqueloux Etienne Simon-Loriere David Veyer Thierry Prazuck Hélène Péré Olivier Schwartz |
| author_facet | Delphine Planas Timothée Bruel Isabelle Staropoli Florence Guivel-Benhassine Françoise Porrot Piet Maes Ludivine Grzelak Matthieu Prot Said Mougari Cyril Planchais Julien Puech Madelina Saliba Riwan Sahraoui Florent Fémy Nathalie Morel Jérémy Dufloo Rafael Sanjuán Hugo Mouquet Emmanuel André Laurent Hocqueloux Etienne Simon-Loriere David Veyer Thierry Prazuck Hélène Péré Olivier Schwartz |
| author_sort | Delphine Planas |
| collection | DOAJ |
| description | In this work, Planas et al. report that Omicron subvariants BA.2.75.2, BA.4.6, and BQ.1.1 escape neutralization from monoclonal antibodies, and sera from vaccinated individuals with or without Omicron BA.1/2 or BA.5 breakthrough infection. |
| first_indexed | 2024-04-09T22:48:26Z |
| format | Article |
| id | doaj.art-9c8be56ed653485d87b24ff59791518f |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-04-09T22:48:26Z |
| publishDate | 2023-02-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-9c8be56ed653485d87b24ff59791518f2023-03-22T11:44:48ZengNature PortfolioNature Communications2041-17232023-02-0114111110.1038/s41467-023-36561-6Resistance of Omicron subvariants BA.2.75.2, BA.4.6, and BQ.1.1 to neutralizing antibodiesDelphine Planas0Timothée Bruel1Isabelle Staropoli2Florence Guivel-Benhassine3Françoise Porrot4Piet Maes5Ludivine Grzelak6Matthieu Prot7Said Mougari8Cyril Planchais9Julien Puech10Madelina Saliba11Riwan Sahraoui12Florent Fémy13Nathalie Morel14Jérémy Dufloo15Rafael Sanjuán16Hugo Mouquet17Emmanuel André18Laurent Hocqueloux19Etienne Simon-Loriere20David Veyer21Thierry Prazuck22Hélène Péré23Olivier Schwartz24Virus and Immunity Unit, Institut Pasteur, Université Paris CitéVirus and Immunity Unit, Institut Pasteur, Université Paris CitéVirus and Immunity Unit, Institut Pasteur, Université Paris CitéVirus and Immunity Unit, Institut Pasteur, Université Paris CitéVirus and Immunity Unit, Institut Pasteur, Université Paris CitéKU Leuven, Department of Microbiology, Immunology and Transplantation, Laboratory of Clinical and Epidemiological VirologyVirus and Immunity Unit, Institut Pasteur, Université Paris CitéG5 Evolutionary Genomics of RNA Viruses, Institut Pasteur, Université Paris CitéG5 Evolutionary Genomics of RNA Viruses, Institut Pasteur, Université Paris CitéHumoral Immunology Laboratory, Institut Pasteur, Université Paris CitéLaboratoire de Virologie, Service de Microbiologie, Hôpital Européen Georges PompidouLaboratoire de Virologie, Service de Microbiologie, Hôpital Européen Georges PompidouLaboratoire de Virologie, Service de Microbiologie, Hôpital Européen Georges PompidouService d’accueil des urgences, Hôpital Européen Georges PompidouService de Pharmacologie et Immunoanalyse (SPI), CEA, INRA, Université Paris-SaclayInstitute for Integrative Systems Biology (I2SysBio), Universitat de València-CSICInstitute for Integrative Systems Biology (I2SysBio), Universitat de València-CSICHumoral Immunology Laboratory, Institut Pasteur, Université Paris CitéUniversity Hospitals Leuven, Department of Laboratory Medicine, National Reference Centre for Respiratory PathogensCHR d’Orléans, Service de Maladies InfectieusesG5 Evolutionary Genomics of RNA Viruses, Institut Pasteur, Université Paris CitéLaboratoire de Virologie, Service de Microbiologie, Hôpital Européen Georges PompidouCHR d’Orléans, Service de Maladies InfectieusesLaboratoire de Virologie, Service de Microbiologie, Hôpital Européen Georges PompidouVirus and Immunity Unit, Institut Pasteur, Université Paris CitéIn this work, Planas et al. report that Omicron subvariants BA.2.75.2, BA.4.6, and BQ.1.1 escape neutralization from monoclonal antibodies, and sera from vaccinated individuals with or without Omicron BA.1/2 or BA.5 breakthrough infection.https://doi.org/10.1038/s41467-023-36561-6 |
| spellingShingle | Delphine Planas Timothée Bruel Isabelle Staropoli Florence Guivel-Benhassine Françoise Porrot Piet Maes Ludivine Grzelak Matthieu Prot Said Mougari Cyril Planchais Julien Puech Madelina Saliba Riwan Sahraoui Florent Fémy Nathalie Morel Jérémy Dufloo Rafael Sanjuán Hugo Mouquet Emmanuel André Laurent Hocqueloux Etienne Simon-Loriere David Veyer Thierry Prazuck Hélène Péré Olivier Schwartz Resistance of Omicron subvariants BA.2.75.2, BA.4.6, and BQ.1.1 to neutralizing antibodies Nature Communications |
| title | Resistance of Omicron subvariants BA.2.75.2, BA.4.6, and BQ.1.1 to neutralizing antibodies |
| title_full | Resistance of Omicron subvariants BA.2.75.2, BA.4.6, and BQ.1.1 to neutralizing antibodies |
| title_fullStr | Resistance of Omicron subvariants BA.2.75.2, BA.4.6, and BQ.1.1 to neutralizing antibodies |
| title_full_unstemmed | Resistance of Omicron subvariants BA.2.75.2, BA.4.6, and BQ.1.1 to neutralizing antibodies |
| title_short | Resistance of Omicron subvariants BA.2.75.2, BA.4.6, and BQ.1.1 to neutralizing antibodies |
| title_sort | resistance of omicron subvariants ba 2 75 2 ba 4 6 and bq 1 1 to neutralizing antibodies |
| url | https://doi.org/10.1038/s41467-023-36561-6 |
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