Intravenous Vitamin C Administration Improved Blood Cell Counts and Health-Related Quality of Life of Patient with History of Relapsed Acute Myeloid Leukaemia

A 52-year-old female presented to Integrated Health Options Clinic in October 2014 with a history of relapsed acute myeloid leukaemia (AML, diagnosed in 2009 and relapsed in 2014). Intravenous(IV) vitamin C therapy was initiated (in 2014) following completion of chemotherapy as an alternative to hae...

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Main Authors: Mike N. Foster, Anitra C. Carr, Alina Antony, Selene Peng, Mike G. Fitzpatrick
Format: Article
Language:English
Published: MDPI AG 2018-07-01
Series:Antioxidants
Subjects:
Online Access:http://www.mdpi.com/2076-3921/7/7/92
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author Mike N. Foster
Anitra C. Carr
Alina Antony
Selene Peng
Mike G. Fitzpatrick
author_facet Mike N. Foster
Anitra C. Carr
Alina Antony
Selene Peng
Mike G. Fitzpatrick
author_sort Mike N. Foster
collection DOAJ
description A 52-year-old female presented to Integrated Health Options Clinic in October 2014 with a history of relapsed acute myeloid leukaemia (AML, diagnosed in 2009 and relapsed in 2014). Intravenous(IV) vitamin C therapy was initiated (in 2014) following completion of chemotherapy as an alternative to haematopoietic stem cell transplantation. IV vitamin C was administered twice weekly at a dose of 70 g/infusion. Within 4 weeks of initiation of IV vitamin C therapy, there was a dramatic improvement in the patient’s blood indices with platelet cell counts increasing from 25 × 109/L to 196 × 109/L and white blood cell counts increasing from 0.29 × 109/L to 4.0 × 109/L, with further improvements observed over the next 18 months. Furthermore, there was a clear and sustained improvement in the patient’s health-related quality of life scores assessed using a validated questionnaire. She has remained healthy and in complete remission until the present day. This case study highlights the benefits of IV vitamin C as a supportive therapy for previously relapsed AML.
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spelling doaj.art-9c8f98fb549f4c01b64adfa518a0c26b2023-09-02T22:23:25ZengMDPI AGAntioxidants2076-39212018-07-01779210.3390/antiox7070092antiox7070092Intravenous Vitamin C Administration Improved Blood Cell Counts and Health-Related Quality of Life of Patient with History of Relapsed Acute Myeloid LeukaemiaMike N. Foster0Anitra C. Carr1Alina Antony2Selene Peng3Mike G. Fitzpatrick4Integrated Health Options Ltd., Auckland 1050, New ZealandDepartment of Pathology and Biomedical Science, University of Otago, Christchurch 8011, New ZealandFeedback Research Ltd., Auckland 1050, New ZealandFeedback Research Ltd., Auckland 1050, New ZealandFeedback Research Ltd., Auckland 1050, New ZealandA 52-year-old female presented to Integrated Health Options Clinic in October 2014 with a history of relapsed acute myeloid leukaemia (AML, diagnosed in 2009 and relapsed in 2014). Intravenous(IV) vitamin C therapy was initiated (in 2014) following completion of chemotherapy as an alternative to haematopoietic stem cell transplantation. IV vitamin C was administered twice weekly at a dose of 70 g/infusion. Within 4 weeks of initiation of IV vitamin C therapy, there was a dramatic improvement in the patient’s blood indices with platelet cell counts increasing from 25 × 109/L to 196 × 109/L and white blood cell counts increasing from 0.29 × 109/L to 4.0 × 109/L, with further improvements observed over the next 18 months. Furthermore, there was a clear and sustained improvement in the patient’s health-related quality of life scores assessed using a validated questionnaire. She has remained healthy and in complete remission until the present day. This case study highlights the benefits of IV vitamin C as a supportive therapy for previously relapsed AML.http://www.mdpi.com/2076-3921/7/7/92vitamin Cintravenous vitamin Cleukemiaacute myeloid leukemiaAML
spellingShingle Mike N. Foster
Anitra C. Carr
Alina Antony
Selene Peng
Mike G. Fitzpatrick
Intravenous Vitamin C Administration Improved Blood Cell Counts and Health-Related Quality of Life of Patient with History of Relapsed Acute Myeloid Leukaemia
Antioxidants
vitamin C
intravenous vitamin C
leukemia
acute myeloid leukemia
AML
title Intravenous Vitamin C Administration Improved Blood Cell Counts and Health-Related Quality of Life of Patient with History of Relapsed Acute Myeloid Leukaemia
title_full Intravenous Vitamin C Administration Improved Blood Cell Counts and Health-Related Quality of Life of Patient with History of Relapsed Acute Myeloid Leukaemia
title_fullStr Intravenous Vitamin C Administration Improved Blood Cell Counts and Health-Related Quality of Life of Patient with History of Relapsed Acute Myeloid Leukaemia
title_full_unstemmed Intravenous Vitamin C Administration Improved Blood Cell Counts and Health-Related Quality of Life of Patient with History of Relapsed Acute Myeloid Leukaemia
title_short Intravenous Vitamin C Administration Improved Blood Cell Counts and Health-Related Quality of Life of Patient with History of Relapsed Acute Myeloid Leukaemia
title_sort intravenous vitamin c administration improved blood cell counts and health related quality of life of patient with history of relapsed acute myeloid leukaemia
topic vitamin C
intravenous vitamin C
leukemia
acute myeloid leukemia
AML
url http://www.mdpi.com/2076-3921/7/7/92
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