Localized scleroderma secondary to mixed connective tissue disease during abatacept therapy

A 47‐year‐old woman with mixed connective tissue disease was treated with abatacept. After 2 months, a 3‐cm depression with atrophied surface was observed on her back, which had histopathological consistent with the symptoms of localized scleroderma. Although some cases of paradoxical reaction or cu...

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Main Authors: Sayuko Nagaoka, Shujiro Hayashi, Ken Igawa
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Journal of Cutaneous Immunology and Allergy
Online Access:https://doi.org/10.1002/cia2.12215
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author Sayuko Nagaoka
Shujiro Hayashi
Ken Igawa
author_facet Sayuko Nagaoka
Shujiro Hayashi
Ken Igawa
author_sort Sayuko Nagaoka
collection DOAJ
description A 47‐year‐old woman with mixed connective tissue disease was treated with abatacept. After 2 months, a 3‐cm depression with atrophied surface was observed on her back, which had histopathological consistent with the symptoms of localized scleroderma. Although some cases of paradoxical reaction or cutaneous adverse event have been reported from abatacept, no localized scleroderma has been reported, suggesting this to be a unique case.
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spelling doaj.art-9c9293a4d21a40b7bb3b96f886df684e2024-02-02T06:10:28ZengFrontiers Media S.A.Journal of Cutaneous Immunology and Allergy2574-45932022-06-0153949610.1002/cia2.12215Localized scleroderma secondary to mixed connective tissue disease during abatacept therapySayuko Nagaoka0Shujiro Hayashi1Ken Igawa2Department of Dermatology Dokkyo Medical University Mibu JapanDepartment of Dermatology Dokkyo Medical University Mibu JapanDepartment of Dermatology Dokkyo Medical University Mibu JapanA 47‐year‐old woman with mixed connective tissue disease was treated with abatacept. After 2 months, a 3‐cm depression with atrophied surface was observed on her back, which had histopathological consistent with the symptoms of localized scleroderma. Although some cases of paradoxical reaction or cutaneous adverse event have been reported from abatacept, no localized scleroderma has been reported, suggesting this to be a unique case.https://doi.org/10.1002/cia2.12215
spellingShingle Sayuko Nagaoka
Shujiro Hayashi
Ken Igawa
Localized scleroderma secondary to mixed connective tissue disease during abatacept therapy
Journal of Cutaneous Immunology and Allergy
title Localized scleroderma secondary to mixed connective tissue disease during abatacept therapy
title_full Localized scleroderma secondary to mixed connective tissue disease during abatacept therapy
title_fullStr Localized scleroderma secondary to mixed connective tissue disease during abatacept therapy
title_full_unstemmed Localized scleroderma secondary to mixed connective tissue disease during abatacept therapy
title_short Localized scleroderma secondary to mixed connective tissue disease during abatacept therapy
title_sort localized scleroderma secondary to mixed connective tissue disease during abatacept therapy
url https://doi.org/10.1002/cia2.12215
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AT shujirohayashi localizedsclerodermasecondarytomixedconnectivetissuediseaseduringabatacepttherapy
AT kenigawa localizedsclerodermasecondarytomixedconnectivetissuediseaseduringabatacepttherapy