Case Report: Ochronotic Arthropathy
Ochronosis is a rare metabolic disease caused by the deficiency of the homogentisic acid oxidase enzyme. It gives clinical findings related to the accumulation of homogentisic acid in soft tissues and excretion in urine. Patients with chronic arthropathy usually have some joint pain and inflammatory...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Galenos Yayinevi
2021-08-01
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| Series: | Forbes Tıp Dergisi |
| Subjects: | |
| Online Access: | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=forbes&un=FJM-32932 |
| _version_ | 1827888894450860032 |
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| author | Ülkü Dönmez Ece Cinar Cihat Ozturk Simin Hepgüler |
| author_facet | Ülkü Dönmez Ece Cinar Cihat Ozturk Simin Hepgüler |
| author_sort | Ülkü Dönmez |
| collection | DOAJ |
| description | Ochronosis is a rare metabolic disease caused by the deficiency of the homogentisic acid oxidase enzyme. It gives clinical findings related to the accumulation of homogentisic acid in soft tissues and excretion in urine. Patients with chronic arthropathy usually have some joint pain and inflammatory back pain. Although axial involvement radiologically resembles ankylosing spondylitis (AS), it is differentiated by the absence of typical syndesmophytes, facet involvement, sacroiliac erosion and fusion.Although there is no effective treatment for ochronosis disease; our patient was given a protein-poor diet, vitamin C supplementation (100 mg/kg/day) and analgesic treatment for symptoms recommended in the literature; and a reduction in joint complaints was observed. In this case, the aim is to diagnose the rare ochronotic arthropathy followed with the diagnosis of AS and to show that both axial and peripheral joint involvement can be together in this disease. |
| first_indexed | 2024-03-12T20:40:21Z |
| format | Article |
| id | doaj.art-9c92f617ccce4364a10902c458008b08 |
| institution | Directory Open Access Journal |
| issn | 2757-5241 |
| language | English |
| last_indexed | 2024-03-12T20:40:21Z |
| publishDate | 2021-08-01 |
| publisher | Galenos Yayinevi |
| record_format | Article |
| series | Forbes Tıp Dergisi |
| spelling | doaj.art-9c92f617ccce4364a10902c458008b082023-08-01T10:47:26ZengGalenos YayineviForbes Tıp Dergisi2757-52412021-08-012213613910.5222/forbes.2021.32932FJM-32932Case Report: Ochronotic ArthropathyÜlkü Dönmez0Ece Cinar1Cihat Ozturk2Simin Hepgüler3Buca Seyfi Demirsoy Training And Research Hospital Physical Medicine And Rehabilitation,izmirEge University Medical School Physical Medicine And Rehabilitation, İzmirEge University Medical School Physical Medicine And Rehabilitation, İzmirEge University Medical School Physical Medicine And Rehabilitation, İzmirOchronosis is a rare metabolic disease caused by the deficiency of the homogentisic acid oxidase enzyme. It gives clinical findings related to the accumulation of homogentisic acid in soft tissues and excretion in urine. Patients with chronic arthropathy usually have some joint pain and inflammatory back pain. Although axial involvement radiologically resembles ankylosing spondylitis (AS), it is differentiated by the absence of typical syndesmophytes, facet involvement, sacroiliac erosion and fusion.Although there is no effective treatment for ochronosis disease; our patient was given a protein-poor diet, vitamin C supplementation (100 mg/kg/day) and analgesic treatment for symptoms recommended in the literature; and a reduction in joint complaints was observed. In this case, the aim is to diagnose the rare ochronotic arthropathy followed with the diagnosis of AS and to show that both axial and peripheral joint involvement can be together in this disease.https://jag.journalagent.com/z4/download_fulltext.asp?pdir=forbes&un=FJM-32932ochronosisarthropathylow back pain |
| spellingShingle | Ülkü Dönmez Ece Cinar Cihat Ozturk Simin Hepgüler Case Report: Ochronotic Arthropathy Forbes Tıp Dergisi ochronosis arthropathy low back pain |
| title | Case Report: Ochronotic Arthropathy |
| title_full | Case Report: Ochronotic Arthropathy |
| title_fullStr | Case Report: Ochronotic Arthropathy |
| title_full_unstemmed | Case Report: Ochronotic Arthropathy |
| title_short | Case Report: Ochronotic Arthropathy |
| title_sort | case report ochronotic arthropathy |
| topic | ochronosis arthropathy low back pain |
| url | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=forbes&un=FJM-32932 |
| work_keys_str_mv | AT ulkudonmez casereportochronoticarthropathy AT ececinar casereportochronoticarthropathy AT cihatozturk casereportochronoticarthropathy AT siminhepguler casereportochronoticarthropathy |