Clinical cases of zoonotic Cryptosporidium parvum (subtype IIdA15G1) infections in Korean goats
Cryptosporidium parvum is an enteric protozoan, which causes severe diarrhoea in a wide range of vertebrate hosts including ruminants and humans. C. parvum infections are responsible for immense economic losses to the livestock industry; furthermore, the zoonotic spread of the infection may lead to...
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| Format: | Article |
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Czech Academy of Agricultural Sciences
2022-03-01
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| Series: | Veterinární Medicína |
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| Online Access: | https://vetmed.agriculturejournals.cz/artkey/vet-202203-0006_clinical-cases-of-zoonotic-cryptosporidium-parvum-subtype-iida15g1-infections-in-korean-goats.php |
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| author | J Kim K Lee Roh SG Kim HY Kim JW So BJ Choi EJ |
| author_facet | J Kim K Lee Roh SG Kim HY Kim JW So BJ Choi EJ |
| author_sort | J Kim |
| collection | DOAJ |
| description | Cryptosporidium parvum is an enteric protozoan, which causes severe diarrhoea in a wide range of vertebrate hosts including ruminants and humans. C. parvum infections are responsible for immense economic losses to the livestock industry; furthermore, the zoonotic spread of the infection may lead to mortality in immunosuppressed humans. In the present study, we report two cases of severe cryptosporidiosis in goat kids in the Republic of Korea. Both cases were afflicted with severe diarrhoea upon presentation; the histopathological examinations revealed atrophied and fused intestinal villi and numerous circular basophilic organisms in the jejunum and ileum. Both cases were diagnosed with cryptosporidiosis based on the results of the histopathological analysis, amplification of the C. parvum gp60 gene, modified Ziehl-Neelsen staining, and C. parvum antigen ELISA. According to the phylogenetic analysis using the C. parvum gp60 gene for the genetic subtypes, the C. parvum isolates were identified as subtype IIdA15G1 with zoonotic potential. This is the first pathological report of caprine cryptosporidiosis induced by C. parvum subtype IId in the Republic of Korea. Considering the clinical manifestations associated with the pathological lesions and the zoonotic significance of these findings, the continuous monitoring and prevention of C. parvum infections in goats are essential for minimising the economic losses in ruminant farms and in maintaining public health safety standards. |
| first_indexed | 2024-04-10T07:57:45Z |
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| id | doaj.art-9c9974ba949a4e329aae64b0346a376a |
| institution | Directory Open Access Journal |
| issn | 0375-8427 1805-9392 |
| language | English |
| last_indexed | 2024-04-10T07:57:45Z |
| publishDate | 2022-03-01 |
| publisher | Czech Academy of Agricultural Sciences |
| record_format | Article |
| series | Veterinární Medicína |
| spelling | doaj.art-9c9974ba949a4e329aae64b0346a376a2023-02-23T03:51:11ZengCzech Academy of Agricultural SciencesVeterinární Medicína0375-84271805-93922022-03-0167315616210.17221/212/2020-VETMEDvet-202203-0006Clinical cases of zoonotic Cryptosporidium parvum (subtype IIdA15G1) infections in Korean goatsJ Kim0K Lee1Roh SG2Kim HY3Kim JW4So BJ5Choi EJ6Animal Disease Diagnostic Division, Animal and Plant Quarantine Agency, Gimcheon, Republic of KoreaAnimal Disease Diagnostic Division, Animal and Plant Quarantine Agency, Gimcheon, Republic of KoreaAnimal Disease Diagnostic Division, Animal and Plant Quarantine Agency, Gimcheon, Republic of KoreaAnimal Disease Diagnostic Division, Animal and Plant Quarantine Agency, Gimcheon, Republic of KoreaAnimal Disease Diagnostic Division, Animal and Plant Quarantine Agency, Gimcheon, Republic of KoreaAnimal Disease Diagnostic Division, Animal and Plant Quarantine Agency, Gimcheon, Republic of KoreaFoot and Mouth Disease Diagnostic Division, Animal and Plant Quarantine Agency, Gimcheon, Republic of KoreaCryptosporidium parvum is an enteric protozoan, which causes severe diarrhoea in a wide range of vertebrate hosts including ruminants and humans. C. parvum infections are responsible for immense economic losses to the livestock industry; furthermore, the zoonotic spread of the infection may lead to mortality in immunosuppressed humans. In the present study, we report two cases of severe cryptosporidiosis in goat kids in the Republic of Korea. Both cases were afflicted with severe diarrhoea upon presentation; the histopathological examinations revealed atrophied and fused intestinal villi and numerous circular basophilic organisms in the jejunum and ileum. Both cases were diagnosed with cryptosporidiosis based on the results of the histopathological analysis, amplification of the C. parvum gp60 gene, modified Ziehl-Neelsen staining, and C. parvum antigen ELISA. According to the phylogenetic analysis using the C. parvum gp60 gene for the genetic subtypes, the C. parvum isolates were identified as subtype IIdA15G1 with zoonotic potential. This is the first pathological report of caprine cryptosporidiosis induced by C. parvum subtype IId in the Republic of Korea. Considering the clinical manifestations associated with the pathological lesions and the zoonotic significance of these findings, the continuous monitoring and prevention of C. parvum infections in goats are essential for minimising the economic losses in ruminant farms and in maintaining public health safety standards.https://vetmed.agriculturejournals.cz/artkey/vet-202203-0006_clinical-cases-of-zoonotic-cryptosporidium-parvum-subtype-iida15g1-infections-in-korean-goats.phpcryptosporidiosisdiarrhoeagoathistopathologyphylogenetic analysiszoonosis |
| spellingShingle | J Kim K Lee Roh SG Kim HY Kim JW So BJ Choi EJ Clinical cases of zoonotic Cryptosporidium parvum (subtype IIdA15G1) infections in Korean goats Veterinární Medicína cryptosporidiosis diarrhoea goat histopathology phylogenetic analysis zoonosis |
| title | Clinical cases of zoonotic Cryptosporidium parvum (subtype IIdA15G1) infections in Korean goats |
| title_full | Clinical cases of zoonotic Cryptosporidium parvum (subtype IIdA15G1) infections in Korean goats |
| title_fullStr | Clinical cases of zoonotic Cryptosporidium parvum (subtype IIdA15G1) infections in Korean goats |
| title_full_unstemmed | Clinical cases of zoonotic Cryptosporidium parvum (subtype IIdA15G1) infections in Korean goats |
| title_short | Clinical cases of zoonotic Cryptosporidium parvum (subtype IIdA15G1) infections in Korean goats |
| title_sort | clinical cases of zoonotic cryptosporidium parvum subtype iida15g1 infections in korean goats |
| topic | cryptosporidiosis diarrhoea goat histopathology phylogenetic analysis zoonosis |
| url | https://vetmed.agriculturejournals.cz/artkey/vet-202203-0006_clinical-cases-of-zoonotic-cryptosporidium-parvum-subtype-iida15g1-infections-in-korean-goats.php |
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