Frequency of Esophageal Motility Disorders in Patients with Non-Cardiac Chest Pain
Background and purpose: Non-cardiac chest pain (NCCP) is a common entity with negative effects on quality of life that places a large financial burden on health systems. This study aimed at investigating esophageal motility disorders in patients with NCCP. Materials and methods: This cross-sectional...
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| Format: | Article |
| Language: | English |
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Mazandaran University of Medical Sciences
2019-10-01
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| Series: | Journal of Mazandaran University of Medical Sciences |
| Subjects: | |
| Online Access: | http://jmums.mazums.ac.ir/article-1-12825-en.html |
| _version_ | 1797943931765260288 |
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| author | Seyed Jalal Hashemi Seyed Ali Fatemi Behbahani Seyed Masood Seyedian |
| author_facet | Seyed Jalal Hashemi Seyed Ali Fatemi Behbahani Seyed Masood Seyedian |
| author_sort | Seyed Jalal Hashemi |
| collection | DOAJ |
| description | Background and purpose: Non-cardiac chest pain (NCCP) is a common entity with negative effects on quality of life that places a large financial burden on health systems. This study aimed at investigating esophageal motility disorders in patients with NCCP.
Materials and methods: This cross-sectional study was conducted in 101 patients with recurrent chest pain without any cardiac disease, attending Ahvaz Imam Khomeini Hospital in a one-year period. Those who had no evidence of gastroesophageal reflux disease (GERD) on upper endoscopy and 24-hr esophageal pH monitoring were referred for conventional esophageal manometry.
Results: From 101 patients, 51 showed endoscopic or pH-metric evidences of GERD. Manometric evaluation was done in 50 patients, including 27 males and 23 females (mean age: 44.2 years, 26-68 years old). Half of the cases (n=25) had abnormal motility disorders, including nonspecific esophageal motility disorder (20%), nutcracker esophagus (10%), diffuse esophageal spasm (8%), hypertensive LES syndrome (8%), and ineffective esophageal motility (4%). Esophageal motility disorders were found to have no significant associations with weight and age (P=0.125 and P=0.285). The rate of esophageal motility disorders were lower in non-smokers (P=0.019).
Conclusion: Esophageal motility disorders and GERD are frequent in patients with NCCP. Further studies are needed to establish a cause-effect relationship. |
| first_indexed | 2024-04-10T20:31:55Z |
| format | Article |
| id | doaj.art-9ca00a6f8a314858aad10da5911e5d0a |
| institution | Directory Open Access Journal |
| issn | 1735-9260 1735-9279 |
| language | English |
| last_indexed | 2024-04-10T20:31:55Z |
| publishDate | 2019-10-01 |
| publisher | Mazandaran University of Medical Sciences |
| record_format | Article |
| series | Journal of Mazandaran University of Medical Sciences |
| spelling | doaj.art-9ca00a6f8a314858aad10da5911e5d0a2023-01-25T06:08:39ZengMazandaran University of Medical SciencesJournal of Mazandaran University of Medical Sciences1735-92601735-92792019-10-0129177139147Frequency of Esophageal Motility Disorders in Patients with Non-Cardiac Chest PainSeyed Jalal Hashemi0Seyed Ali Fatemi Behbahani1Seyed Masood Seyedian2 Associate Professor, Department of Internal Medicine, School of Medicine, Alimentary Tract Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran Assistant Professor, Department of Internal Medicine, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran Assistant Professor, Department of Cardiology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran Background and purpose: Non-cardiac chest pain (NCCP) is a common entity with negative effects on quality of life that places a large financial burden on health systems. This study aimed at investigating esophageal motility disorders in patients with NCCP. Materials and methods: This cross-sectional study was conducted in 101 patients with recurrent chest pain without any cardiac disease, attending Ahvaz Imam Khomeini Hospital in a one-year period. Those who had no evidence of gastroesophageal reflux disease (GERD) on upper endoscopy and 24-hr esophageal pH monitoring were referred for conventional esophageal manometry. Results: From 101 patients, 51 showed endoscopic or pH-metric evidences of GERD. Manometric evaluation was done in 50 patients, including 27 males and 23 females (mean age: 44.2 years, 26-68 years old). Half of the cases (n=25) had abnormal motility disorders, including nonspecific esophageal motility disorder (20%), nutcracker esophagus (10%), diffuse esophageal spasm (8%), hypertensive LES syndrome (8%), and ineffective esophageal motility (4%). Esophageal motility disorders were found to have no significant associations with weight and age (P=0.125 and P=0.285). The rate of esophageal motility disorders were lower in non-smokers (P=0.019). Conclusion: Esophageal motility disorders and GERD are frequent in patients with NCCP. Further studies are needed to establish a cause-effect relationship.http://jmums.mazums.ac.ir/article-1-12825-en.htmlnon cardiac chest paingastroesophageal refluxesophageal motility |
| spellingShingle | Seyed Jalal Hashemi Seyed Ali Fatemi Behbahani Seyed Masood Seyedian Frequency of Esophageal Motility Disorders in Patients with Non-Cardiac Chest Pain Journal of Mazandaran University of Medical Sciences non cardiac chest pain gastroesophageal reflux esophageal motility |
| title | Frequency of Esophageal Motility Disorders in Patients
with Non-Cardiac Chest Pain |
| title_full | Frequency of Esophageal Motility Disorders in Patients
with Non-Cardiac Chest Pain |
| title_fullStr | Frequency of Esophageal Motility Disorders in Patients
with Non-Cardiac Chest Pain |
| title_full_unstemmed | Frequency of Esophageal Motility Disorders in Patients
with Non-Cardiac Chest Pain |
| title_short | Frequency of Esophageal Motility Disorders in Patients
with Non-Cardiac Chest Pain |
| title_sort | frequency of esophageal motility disorders in patients with non cardiac chest pain |
| topic | non cardiac chest pain gastroesophageal reflux esophageal motility |
| url | http://jmums.mazums.ac.ir/article-1-12825-en.html |
| work_keys_str_mv | AT seyedjalalhashemi frequencyofesophagealmotilitydisordersinpatientswithnoncardiacchestpain AT seyedalifatemibehbahani frequencyofesophagealmotilitydisordersinpatientswithnoncardiacchestpain AT seyedmasoodseyedian frequencyofesophagealmotilitydisordersinpatientswithnoncardiacchestpain |