Dissecting the pre-placodal transcriptome to reveal presumptive direct targets of Six1 and Eya1 in cranial placodes
The pre-placodal ectoderm, marked by the expression of the transcription factor Six1 and its co-activator Eya1, develops into placodes and ultimately into many cranial sensory organs and ganglia. Using RNA-Seq in Xenopus laevis we screened for presumptive direct placodal target genes of Six1 and Eya...
Main Authors: | Nick Riddiford, Gerhard Schlosser |
---|---|
Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2016-08-01
|
Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/17666 |
Similar Items
-
Six1 proteins with human branchio-oto-renal mutations differentially affect cranial gene expression and otic development
by: Ankita M. Shah, et al.
Published: (2020-03-01) -
Npr3 regulates neural crest and cranial placode progenitors formation through its dual function as clearance and signaling receptor
by: Arun Devotta, et al.
Published: (2023-05-01) -
An Eya1-Notch axis specifies bipotential epibranchial differentiation in mammalian craniofacial morphogenesis
by: Haoran Zhang, et al.
Published: (2017-11-01) -
SIX1 Activates STAT3 Signaling to Promote the Proliferation of Thyroid Carcinoma via EYA1
by: Deguang Kong, et al.
Published: (2019-12-01) -
Otic Neurogenesis in Xenopus laevis: Proliferation, Differentiation, and the Role of Eya1
by: Suad Hamdan Almasoudi, et al.
Published: (2021-09-01)