Expression of SARS-CoV-2 Spike Protein Receptor Binding Domain on Recombinant <i>B. subtilis</i> on Spore Surface: A Potential COVID-19 Oral Vaccine Candidate

Expression of SARS-CoV-2 Spike Protein Receptor Binding Domain on Recombinant <i>B. subtilis</i> on Spore Surface: A Potential COVID-19 Oral Vaccine Candidate

Various types of vaccines, such as mRNA, adenovirus, and inactivated virus by injection, have been developed to prevent SARS-CoV-2 infection. Although some of them have already been approved under the COVID-19 pandemic, various drawbacks, including severe side effects and the requirement for sub-zer...

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Bibliographic Details
Main Authors: Johnny Chun-Chau Sung, Ying Liu, Kam-Chau Wu, Man-Chung Choi, Chloe Ho-Yi Ma, Jayman Lin, Emily Isabel Cheng He, David Yiu-Ming Leung, Eric Tung-Po Sze, Yusuf Khwaja Hamied, Dominic Man-Kit Lam, Keith Wai-Yeung Kwong
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Vaccines
Subjects:
SARS-CoV-2
COVID-19
oral vaccine
<i>Bacillus subtilis</i>
spike protein
sporulation
Online Access:https://www.mdpi.com/2076-393X/10/1/2

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