Biomarkers of acute myocardial infarction: diagnostic and prognostic value. Part 2 (Literature review)

In the second part of the review, we continue the discussion of biomarkers that have a diagnostic and prognostic significance in acute myocardial infarction (AMI). The study of the AMI pathophysiology through the experimental and clinical research contributes to the discovery of new regulatory molec...

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Main Authors: Aleksey M. Chaulin, Dmitry V. Duplyakov
Format: Article
Language:English
Published: Eco-vector 2020-12-01
Series:Клиническая практика
Subjects:
Online Access:https://journals.eco-vector.com/clinpractice/article/viewFile/48893/pdf
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author Aleksey M. Chaulin
Dmitry V. Duplyakov
author_facet Aleksey M. Chaulin
Dmitry V. Duplyakov
author_sort Aleksey M. Chaulin
collection DOAJ
description In the second part of the review, we continue the discussion of biomarkers that have a diagnostic and prognostic significance in acute myocardial infarction (AMI). The study of the AMI pathophysiology through the experimental and clinical research contributes to the discovery of new regulatory molecules and pathogenetic mechanisms underlying AMI. At the same time, many molecules involved in the pathogenesis of AMI can be used as effective biomarkers for the diagnosis and prediction of AMI. This article discusses in detail the diagnostic and prognostic value of inflammatory biomarkers of AMI (C-reactive protein, interleukin-6, tumor necrosis factor-alpha, myeloperoxidase, matrix metalloproteinases, soluble form of CD40 ligand, procalcitonin, placental growth factor) and a number of recently discovered new biomarkers of AMI (microribonucleic acids, galectin-3, stimulating growth factor expressed by gene 2, growth differentiation factor 15, proprotein convertase of subtilisin-kexin type 9).
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spelling doaj.art-9caeff6ac12d403cb95833fecf8d09532023-09-02T10:37:16ZengEco-vectorКлиническая практика2220-30952618-86272020-12-01114708210.17816/clinpract4889353294Biomarkers of acute myocardial infarction: diagnostic and prognostic value. Part 2 (Literature review)Aleksey M. Chaulin0https://orcid.org/0000-0002-2712-0227Dmitry V. Duplyakov1https://orcid.org/0000-0002-6453-2976Samara Regional Cardiology DispensarySamara Regional Cardiology DispensaryIn the second part of the review, we continue the discussion of biomarkers that have a diagnostic and prognostic significance in acute myocardial infarction (AMI). The study of the AMI pathophysiology through the experimental and clinical research contributes to the discovery of new regulatory molecules and pathogenetic mechanisms underlying AMI. At the same time, many molecules involved in the pathogenesis of AMI can be used as effective biomarkers for the diagnosis and prediction of AMI. This article discusses in detail the diagnostic and prognostic value of inflammatory biomarkers of AMI (C-reactive protein, interleukin-6, tumor necrosis factor-alpha, myeloperoxidase, matrix metalloproteinases, soluble form of CD40 ligand, procalcitonin, placental growth factor) and a number of recently discovered new biomarkers of AMI (microribonucleic acids, galectin-3, stimulating growth factor expressed by gene 2, growth differentiation factor 15, proprotein convertase of subtilisin-kexin type 9).https://journals.eco-vector.com/clinpractice/article/viewFile/48893/pdflaboratory diagnosticsacute myocardial infarctionamibiomarkersc-reactive proteininterleukin-6tumor necrosis factor-alphamyeloperoxidasematrix metalloproteinasesprocalcitoninmicroribonucleic acidsgalectin-3proprotein convertase subtilisin-kexin type 9
spellingShingle Aleksey M. Chaulin
Dmitry V. Duplyakov
Biomarkers of acute myocardial infarction: diagnostic and prognostic value. Part 2 (Literature review)
Клиническая практика
laboratory diagnostics
acute myocardial infarction
ami
biomarkers
c-reactive protein
interleukin-6
tumor necrosis factor-alpha
myeloperoxidase
matrix metalloproteinases
procalcitonin
microribonucleic acids
galectin-3
proprotein convertase subtilisin-kexin type 9
title Biomarkers of acute myocardial infarction: diagnostic and prognostic value. Part 2 (Literature review)
title_full Biomarkers of acute myocardial infarction: diagnostic and prognostic value. Part 2 (Literature review)
title_fullStr Biomarkers of acute myocardial infarction: diagnostic and prognostic value. Part 2 (Literature review)
title_full_unstemmed Biomarkers of acute myocardial infarction: diagnostic and prognostic value. Part 2 (Literature review)
title_short Biomarkers of acute myocardial infarction: diagnostic and prognostic value. Part 2 (Literature review)
title_sort biomarkers of acute myocardial infarction diagnostic and prognostic value part 2 literature review
topic laboratory diagnostics
acute myocardial infarction
ami
biomarkers
c-reactive protein
interleukin-6
tumor necrosis factor-alpha
myeloperoxidase
matrix metalloproteinases
procalcitonin
microribonucleic acids
galectin-3
proprotein convertase subtilisin-kexin type 9
url https://journals.eco-vector.com/clinpractice/article/viewFile/48893/pdf
work_keys_str_mv AT alekseymchaulin biomarkersofacutemyocardialinfarctiondiagnosticandprognosticvaluepart2literaturereview
AT dmitryvduplyakov biomarkersofacutemyocardialinfarctiondiagnosticandprognosticvaluepart2literaturereview