Prognostic value of combined preoperative phase angle and handgrip strength in cardiac surgery
Abstract Objectives Phase angle (PA) constitutes a bioelectrical impedance measurement, indicating cell membrane health and integrity, hydration, and nutritional status. Handgrip strength (HS) has been also associated with body composition, nutritional status, inflammation, and functional ability in...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2022-09-01
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| Series: | Journal of Cardiothoracic Surgery |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13019-022-01970-z |
| _version_ | 1798032573529587712 |
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| author | Mairi Panagidi Αndreas S. Papazoglou Dimitrios V. Moysidis Elpiniki Vlachopoulou Marios Papadakis Evangelia Kouidi Antonios Galanos Georgios Tagarakis Kyriakos Anastasiadis |
| author_facet | Mairi Panagidi Αndreas S. Papazoglou Dimitrios V. Moysidis Elpiniki Vlachopoulou Marios Papadakis Evangelia Kouidi Antonios Galanos Georgios Tagarakis Kyriakos Anastasiadis |
| author_sort | Mairi Panagidi |
| collection | DOAJ |
| description | Abstract Objectives Phase angle (PA) constitutes a bioelectrical impedance measurement, indicating cell membrane health and integrity, hydration, and nutritional status. Handgrip strength (HS) has been also associated with body composition, nutritional status, inflammation, and functional ability in several chronic diseases. Although their prognostic significance as independent biomarkers has been already investigated regarding the outcomes of a cardiac surgery, our study is the first one to assess the combined predictive value of preoperative PA and HS. Design and methods HS and PA measurements were performed preoperativelyin 195 patients undergoing cardiac surgery. The association ofthe combination of HS and PAwith all-cause mortality rates was the primary study outcome, while its association with the intensive care unit (ICU) length of stay (LOS) was the secondary one. Results PA was positively correlated with HS (r = 0.446, p < 0.005) and negatively with EuroSCORE II (r = − 0.306 p < 0.005). The combination of PA < 5.15 and HS < 25.5 was associated with higher one-year all-cause mortality (OR = 9.28; 95% CI 2.50–34.45; p = 0.001) compared to patients with PA > 5.15 and HS > 25.5, respectively. Patients with combined lower values of PA and HS (PA < 5.15 and HS < 30.7) were at higher risk of prolonged ICU LOS (OR = 4.02; 95% CI 1.53–10.56; p = 0.005) compared to those with higher PA–HS (PA > 5.15–HS > 30.7). The combination of PA–HS was also significantly linked with EuroSCORE II. Conclusion The combination of low preoperative PA and HS values was significantly associated with higher risk of all-cause mortality at 12 months and prolonged ICU LOS; thereby it might serve as a clinically useful prognostic biomarker after cardiac surgery procedures. |
| first_indexed | 2024-04-11T20:14:51Z |
| format | Article |
| id | doaj.art-9cb201b4c33b41168309006051d08e81 |
| institution | Directory Open Access Journal |
| issn | 1749-8090 |
| language | English |
| last_indexed | 2024-04-11T20:14:51Z |
| publishDate | 2022-09-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Cardiothoracic Surgery |
| spelling | doaj.art-9cb201b4c33b41168309006051d08e812022-12-22T04:04:59ZengBMCJournal of Cardiothoracic Surgery1749-80902022-09-011711710.1186/s13019-022-01970-zPrognostic value of combined preoperative phase angle and handgrip strength in cardiac surgeryMairi Panagidi0Αndreas S. Papazoglou1Dimitrios V. Moysidis2Elpiniki Vlachopoulou3Marios Papadakis4Evangelia Kouidi5Antonios Galanos6Georgios Tagarakis7Kyriakos Anastasiadis8Department of Cardiothoracic Surgery, AHEPA University Hospitalof ThessalonikiFirst Department of Cardiology, AHEPA University Hospital of ThessalonikiFirst Department of Cardiology, AHEPA University Hospital of ThessalonikiDepartment of Nutritional Sciences, International Hellenic UniversityUniversity Witten-HerdeckeLaboratory of Sports Medicine, Department of Physical Education and Sports Sciences, Aristotle University of ThessalonikiDepartment of Medicine, National and Kapodistrian University of AthensDepartment of Cardiothoracic Surgery, AHEPA University Hospitalof ThessalonikiDepartment of Cardiothoracic Surgery, AHEPA University Hospitalof ThessalonikiAbstract Objectives Phase angle (PA) constitutes a bioelectrical impedance measurement, indicating cell membrane health and integrity, hydration, and nutritional status. Handgrip strength (HS) has been also associated with body composition, nutritional status, inflammation, and functional ability in several chronic diseases. Although their prognostic significance as independent biomarkers has been already investigated regarding the outcomes of a cardiac surgery, our study is the first one to assess the combined predictive value of preoperative PA and HS. Design and methods HS and PA measurements were performed preoperativelyin 195 patients undergoing cardiac surgery. The association ofthe combination of HS and PAwith all-cause mortality rates was the primary study outcome, while its association with the intensive care unit (ICU) length of stay (LOS) was the secondary one. Results PA was positively correlated with HS (r = 0.446, p < 0.005) and negatively with EuroSCORE II (r = − 0.306 p < 0.005). The combination of PA < 5.15 and HS < 25.5 was associated with higher one-year all-cause mortality (OR = 9.28; 95% CI 2.50–34.45; p = 0.001) compared to patients with PA > 5.15 and HS > 25.5, respectively. Patients with combined lower values of PA and HS (PA < 5.15 and HS < 30.7) were at higher risk of prolonged ICU LOS (OR = 4.02; 95% CI 1.53–10.56; p = 0.005) compared to those with higher PA–HS (PA > 5.15–HS > 30.7). The combination of PA–HS was also significantly linked with EuroSCORE II. Conclusion The combination of low preoperative PA and HS values was significantly associated with higher risk of all-cause mortality at 12 months and prolonged ICU LOS; thereby it might serve as a clinically useful prognostic biomarker after cardiac surgery procedures.https://doi.org/10.1186/s13019-022-01970-zCardiac surgeryPhase angleHandgrip strengthCoronary artery bypass graftingAll-cause mortality |
| spellingShingle | Mairi Panagidi Αndreas S. Papazoglou Dimitrios V. Moysidis Elpiniki Vlachopoulou Marios Papadakis Evangelia Kouidi Antonios Galanos Georgios Tagarakis Kyriakos Anastasiadis Prognostic value of combined preoperative phase angle and handgrip strength in cardiac surgery Journal of Cardiothoracic Surgery Cardiac surgery Phase angle Handgrip strength Coronary artery bypass grafting All-cause mortality |
| title | Prognostic value of combined preoperative phase angle and handgrip strength in cardiac surgery |
| title_full | Prognostic value of combined preoperative phase angle and handgrip strength in cardiac surgery |
| title_fullStr | Prognostic value of combined preoperative phase angle and handgrip strength in cardiac surgery |
| title_full_unstemmed | Prognostic value of combined preoperative phase angle and handgrip strength in cardiac surgery |
| title_short | Prognostic value of combined preoperative phase angle and handgrip strength in cardiac surgery |
| title_sort | prognostic value of combined preoperative phase angle and handgrip strength in cardiac surgery |
| topic | Cardiac surgery Phase angle Handgrip strength Coronary artery bypass grafting All-cause mortality |
| url | https://doi.org/10.1186/s13019-022-01970-z |
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