Integrated Analysis of Single-Cell and Bulk RNA-Sequencing Reveals a Tissue-Resident Macrophage-Related Signature for Predicting Immunotherapy Response in Breast Cancer Patients

Integrated Analysis of Single-Cell and Bulk RNA-Sequencing Reveals a Tissue-Resident Macrophage-Related Signature for Predicting Immunotherapy Response in Breast Cancer Patients

Immune checkpoint therapy (ICT) is among the widely used treatments for breast cancer (BC), but most patients do not respond to ICT and the availability of the predictive biomarkers is limited. Emerging evidence indicates that tissue-resident macrophages (RTMs) inhibit BC progression, suggesting tha...

Full description

Bibliographic Details
Main Authors: Zi-An Xia, You Zhou, Jun Li, Jiang He
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Cancers
Subjects:
breast cancer
immune checkpoint therapy
tissue-resident macrophages
single-cell RNA-sequencing
Online Access:https://www.mdpi.com/2072-6694/14/22/5506

Internet

https://www.mdpi.com/2072-6694/14/22/5506

Similar Items