Genome deletions to overcome the directed loss of gene function in Leishmania
With the global reach of the Neglected Tropical Disease leishmaniasis increasing, coupled with a tiny armory of therapeutics which all have problems with resistance, cost, toxicity and/or administration, the validation of new drug targets in the causative insect vector borne protozoa Leishmania spp...
| Main Authors: | Edubiel A. Alpizar-Sosa, Yasmine Kumordzi, Wenbin Wei, Phillip D. Whitfield, Michael P. Barrett, Paul W. Denny |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2022-09-01
|
| Series: | Frontiers in Cellular and Infection Microbiology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fcimb.2022.988688/full |
Similar Items
-
Glucose Transporters and Virulence in <italic toggle="yes">Leishmania mexicana</italic>
by: Xiuhong Feng, et al.
Published: (2018-08-01) -
On Leishmania enriettii and Other Enigmatic Leishmania Species of the Neotropics
by: Ralph Lainson
Published: (1997-05-01) -
Downregulation of FeSOD-A expression in Leishmania infantum alters trivalent antimony and miltefosine susceptibility
by: Ana Maria Murta Santi, et al.
Published: (2021-07-01) -
Deletion of Glutamine Synthetase Gene Disrupts the Survivability and Infectivity of Leishmania donovani
by: Vinay Kumar, et al.
Published: (2021-02-01) -
Resolution and pro-resolving lipid mediators in Leishmania infection
by: Negar Seyed, et al.
Published: (2019-07-01)