TOPK promotes the growth of esophageal cancer in vitro and in vivo by enhancing YB1/eEF1A1 signal pathway

TOPK promotes the growth of esophageal cancer in vitro and in vivo by enhancing YB1/eEF1A1 signal pathway

Abstract T-LAK-originated protein kinase (TOPK), a dual specificity serine/threonine kinase, is up-regulated and related to poor prognosis in many types of cancers. Y-box binding protein 1 (YB1) is a DNA/RNA binding protein and serves important roles in multiple cellular processes. Here, we reported...

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Bibliographic Details
Main Authors: Wenjie Wu, Jialuo Xu, Dan Gao, Zhenliang Xie, Wenjing Chen, Wenjing Li, Qiang Yuan, Lina Duan, Yuhan Zhang, Xiaoxiao Yang, Yingying Chen, Ziming Dong, Kangdong Liu, Yanan Jiang
Format: Article
Language:English
Published: Nature Publishing Group 2023-06-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-023-05883-0

Internet

https://doi.org/10.1038/s41419-023-05883-0

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