Incidence and mortality of bone cancer among children, adolescents and young adults of Brazil
OBJECTIVES: Bone cancers occur frequently in children, adolescents, and young adults aging 15 to 29 years. Osteosarcoma and Ewing sarcoma are the most frequent subtypes in this population. The aim of this study was to describe incidence and mortality trends of bone cancers among Brazilian children,...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier España
2019-05-01
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| Series: | Clinics |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322019000100229&lng=en&tlng=en |
| _version_ | 1811317101897449472 |
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| author | Nathalie Vieira Balmant Rejane de Souza Reis Marceli de Oliveira Santos Mariana Maschietto Beatriz de Camargo |
| author_facet | Nathalie Vieira Balmant Rejane de Souza Reis Marceli de Oliveira Santos Mariana Maschietto Beatriz de Camargo |
| author_sort | Nathalie Vieira Balmant |
| collection | DOAJ |
| description | OBJECTIVES: Bone cancers occur frequently in children, adolescents, and young adults aging 15 to 29 years. Osteosarcoma and Ewing sarcoma are the most frequent subtypes in this population. The aim of this study was to describe incidence and mortality trends of bone cancers among Brazilian children, adolescents and young adults. METHODS: Incidence information was obtained from 23 population-based cancer registries. Mortality data were extracted from the Atlas of Cancer Mortality from 1979 to 2013. Specific and adjusted rates per million were analyzed according to gender, morphology and age at diagnosis. Median rates were used as a measure of central tendency. Joinpoint regression was applied to analyze trends. RESULTS: Median incidence rates were 5.74 and 11.25 cases per million in children and young adults respectively. Osteosarcoma in the 15-19 years aged group had the highest incidence rates. Stable incidence rates were observed among five registries in 0-14 year's age group. Four registries had a decreased incidence trend among adolescents and young adults. Median mortality rates were 1.22 and 5.07 deaths per million in children and young adults respectively. Increased mortality was observed on the North and Northeast regions. Decreased mortality trends were seen in the South (children) and Southeast (adolescents and young adults). CONCLUSION: Osteosarcoma and Ewing Sarcoma are the most incident bone cancers in all Brazilian regions. Bone cancers showed incidence and mortality patterns variation within the geographic regions and across age groups, although not significant. Despite limitations, it is crucial to monitor cancer epidemiology trends across geographic Brazilian regions. |
| first_indexed | 2024-04-13T12:00:43Z |
| format | Article |
| id | doaj.art-9cb642ff6470489dae8f49d9ba8d73b3 |
| institution | Directory Open Access Journal |
| issn | 1980-5322 |
| language | English |
| last_indexed | 2024-04-13T12:00:43Z |
| publishDate | 2019-05-01 |
| publisher | Elsevier España |
| record_format | Article |
| series | Clinics |
| spelling | doaj.art-9cb642ff6470489dae8f49d9ba8d73b32022-12-22T02:47:47ZengElsevier EspañaClinics1980-53222019-05-0174010.6061/clinics/2019/e858S1807-59322019000100229Incidence and mortality of bone cancer among children, adolescents and young adults of BrazilNathalie Vieira BalmantRejane de Souza ReisMarceli de Oliveira SantosMariana MaschiettoBeatriz de CamargoOBJECTIVES: Bone cancers occur frequently in children, adolescents, and young adults aging 15 to 29 years. Osteosarcoma and Ewing sarcoma are the most frequent subtypes in this population. The aim of this study was to describe incidence and mortality trends of bone cancers among Brazilian children, adolescents and young adults. METHODS: Incidence information was obtained from 23 population-based cancer registries. Mortality data were extracted from the Atlas of Cancer Mortality from 1979 to 2013. Specific and adjusted rates per million were analyzed according to gender, morphology and age at diagnosis. Median rates were used as a measure of central tendency. Joinpoint regression was applied to analyze trends. RESULTS: Median incidence rates were 5.74 and 11.25 cases per million in children and young adults respectively. Osteosarcoma in the 15-19 years aged group had the highest incidence rates. Stable incidence rates were observed among five registries in 0-14 year's age group. Four registries had a decreased incidence trend among adolescents and young adults. Median mortality rates were 1.22 and 5.07 deaths per million in children and young adults respectively. Increased mortality was observed on the North and Northeast regions. Decreased mortality trends were seen in the South (children) and Southeast (adolescents and young adults). CONCLUSION: Osteosarcoma and Ewing Sarcoma are the most incident bone cancers in all Brazilian regions. Bone cancers showed incidence and mortality patterns variation within the geographic regions and across age groups, although not significant. Despite limitations, it is crucial to monitor cancer epidemiology trends across geographic Brazilian regions.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322019000100229&lng=en&tlng=enBrazilIncidenceMortalityBone CancerChildrenAdolescentsYoung Adults |
| spellingShingle | Nathalie Vieira Balmant Rejane de Souza Reis Marceli de Oliveira Santos Mariana Maschietto Beatriz de Camargo Incidence and mortality of bone cancer among children, adolescents and young adults of Brazil Clinics Brazil Incidence Mortality Bone Cancer Children Adolescents Young Adults |
| title | Incidence and mortality of bone cancer among children, adolescents and young adults of Brazil |
| title_full | Incidence and mortality of bone cancer among children, adolescents and young adults of Brazil |
| title_fullStr | Incidence and mortality of bone cancer among children, adolescents and young adults of Brazil |
| title_full_unstemmed | Incidence and mortality of bone cancer among children, adolescents and young adults of Brazil |
| title_short | Incidence and mortality of bone cancer among children, adolescents and young adults of Brazil |
| title_sort | incidence and mortality of bone cancer among children adolescents and young adults of brazil |
| topic | Brazil Incidence Mortality Bone Cancer Children Adolescents Young Adults |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322019000100229&lng=en&tlng=en |
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